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Related Episodes for Nicotinamide mononucleotide cancer study (senescent-cell dependent pancreatic cancer model)

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Why Looking Lean Does Not Rule Out Visceral Fat

Mar 30, 2026

“Imaging studies also associate higher visceral fat with increased cancer incidence in some populations, while large cohort analyses link greater waist circumference with higher all-cause mortality.”

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Why Vigorous Activity Delivers More Benefit per Minute

May 25, 2026

“In more than 25,000 adults who reported no structured exercise, about three short vigorous bouts per day were associated with 38 to 40 percent lower all-cause and cancer mortality and 48 to 49 percent lower cardiovascular mortality compared with no vigorous bouts.”

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Aliquot #101: How Omega-3s Combat Age-Related Muscle Atrophy

Jan 30, 2024

“Rebuilding muscle relies on proper nutrition and exercise, but aging reduces the body's response to both. Extended periods of inactivity, such as post-surgery or during illness, can rapidly deplete muscle mass, especially in older people, potentially pushing them into a "catabolic crisis."”

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Duration: 31m 37s
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Aliquot #102: The Future of Aging Therapeutics, Part 1

Feb 14, 2024

“Scientists are exploring a wide range of cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”

aliquot epigenetics aging stem cells
Duration: 31m 40s
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Aliquot #144: How to Slow Joint Degeneration

Feb 27, 2026

“In this Aliquot, I'm joined by Drs. Martin Gibala, Luc van Loon, and Brad Schoenfeld to break down how to manage load, train in joint-friendly ways, reduce inflammation, and separate supplements supported by evidence from those that remain uncertain.”

aliquot omega-3 inflammation aging
Duration: 44m 31s
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Aliquot #145: How to Protect Immune Function With Age

Apr 8, 2026

“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”

aliquot inflammation immune system cold stress
Duration: 34m 48s
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Aliquot #148: The Hype and Reality of Nicotinamide Riboside

Jul 13, 2026

“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”

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Duration: 45m 35s
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Aliquot #149: The Biology of a Better Mood

Jul 31, 2026

“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”

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Aliquot #36: Inflammation and Depression, part 2 (adding to aliquot #4)

Aug 3, 2021

“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”

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Aliquot #39: Ketogenic Diet Part I: Brain Benefits

Oct 4, 2021

“Eating a typical Western diet – high in processed foods and sugar-sweetened beverages – raises blood glucose and insulin levels, promotes inflammation, and contributes to many neurological disorders, including Alzheimer's disease.”

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