Related Episodes for How Micronutrient Gaps Affect Brain Health

“In this clip from Dr. Rhonda Patrick's appearance on Modern Wisdom, she explains how a large post-meal glucose rise and fall can contribute to the sluggish feeling people call brain fog. Food order offers one practical lever.”

“Aging in tumor tissue is markedly accelerated, however – an indicator of the perturbed metabolic and growth processes observed in cancer. In this clip, Dr. Steve Horvath discusses correlations between epigenetic aging and age-related chronic diseases.”

“Recent studies have identified a connection between an impaired interferon response and severe COVID-19 disease. Strategies that increase the body's core temperature – analogous to having a fever – may be beneficial early in COVID-19 illness.”

“In a two-year trial of 237 postmenopausal women, approximately 9 to 10 grams per day combined with resistance training and walking did not add a bone-density benefit, so its role is better framed around muscle and physical function.”

“Contrary to the traditional view of lactate as a metabolic waste product, it is now recognized for its critical role in brain health. Elevated lactate levels after vigorous exercise are linked to improved executive function, hinting at its potential protective benefits against neurodegenerative diseases.”

“A 2023 network meta-analysis of 270 randomized trials found average reductions after aerobic, dynamic resistance, combined, high-intensity interval, and isometric training, with the largest pooled estimate for isometric exercise.”

“Dr. Patrick also describes a proposed anti-metastatic mechanism: faster blood flow during vigorous exercise increases shear forces on circulating tumor cells, the cells that have left a primary tumor and entered the bloodstream.”

“Controlled human studies support acute brain-related responses to high-intensity exercise. Six short all-out cycling intervals improved selected learning and executive measures while increasing circulating BDNF, IGF-1, and VEGF; lactate tracked several of these changes.”

“Exercise can improve blood pressure, insulin sensitivity, triglycerides, and fitness, but someone with high ApoB or LDL may still need targeted diet changes and clinician-guided lipid-lowering treatment. Mood is another major benefit.”

“Mounting evidence suggests that exploiting this property may be useful towards reducing the toxicity of chemotherapeutics while also maximizing their impact in the treatment of cancer.”