Related Episodes for Preferential fuel resources for the brain: ketones in context | Dominic D’Agostino

“Genetic predisposition, altered glucose uptake in the brain, high blood pressure, and other factors can weaken the barrier's integrity, allowing endotoxins and inflammatory immune cells to infiltrate the brain and increasing a person's risk for dementia.”

“Animal studies indicate that omega-3 deficiency may also reduce GLUT1 transporters in the brain. Other studies suggest that omega-3 supplementation reduces VCAM1 levels – a protein elevated with normal aging, which could be related to the breakdown of the blood-brain barrier.”

“Approximately 25 percent of people in the United States – roughly 75 million people – carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

“- Arthur Brooks, Ph.D. The episode closes with a framework from Brooks's work on the second half of life: jump, serve, worship, and connect, a framework he outlines in one of his earlier books, From Strength to Strength: "Jump" means proactively building the next thing, especially during liminal periods or unwelcome change, which Brooks sees as fertile ground for creativity.”

“Since a driving force in the development of insomnia is change, especially change that affects relationships, employment, or family dynamics, Dr. Mason employs cognitive behavior techniques that help her patients identify what those changes are and develop strategies that promote, rather than hinder, sleep.”

“Breast milk contains a diverse and highly complex community of microbes that come from a variety of sources. Exposure to this community may contribute to the differences observed in gut microbial populations between breastfed and formula-fed infants. In this clip, Dr. Rhonda Patrick describes the unique community of microbes present in human breast milk.”

“Practicing the skills they acquire with resources available in the community — a personal trainer or a group class will allow them to reap the benefits of exercise. People are encouraged to try a variety of activities, which can improve their enjoyment and compliance.”

“Dr. Patrick treats magnesium L-threonate separately. Early human findings are limited by small studies, industry funding, and products that sometimes include coingredients, making it difficult to attribute effects to L-threonate alone.”

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”