Related Episodes for Prolonged fasting and fasting-mimicking preferentially deplete visceral fat rather than lean mass

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Diamandis and Robbins are a dynamic duo, having paired up with co-author Dr. Robert Hariri to write Life Force, a best-selling book that describes breakthroughs in precision medicine and health technologies that can help people live longer, healthier, more fulfilling lives – in the very near future.”

“In this video, Dr. Rhonda Patrick summarizes a recent study that found that frequency of sauna use was associated with increased decreased risk of death. Using the sauna 2-3 times per week was associated with 24% lower all-cause mortality and 4-7 times per week decreased all-cause mortality by 40%.”

“In this Knowledge Project excerpt, Dr. Rhonda Patrick distinguishes Finnish sauna protocols near 174–175°F from lower-temperature infrared sauna, which may require longer exposure. Dose depends on temperature, humidity, duration, acclimation, hydration, and health.”

“Although whole-body hyperthermia and sauna use share some similarities, whole-body hyperthermia sessions are typically longer (an hour or more) and the participant's head is spared (often kept cool with ice or cool cloths), prolonging the participant's tolerance to the intense heat.”

“A staggering 60% of all calories Americans consume come from ultra-processed foods that fail to induce proper satiety, remain cheaper than whole foods, and hijack our dopamine reward pathways, pushing us to overeat, incentivizing unhealthy food choices, and reinforcing addictive eating behaviors.”

“Exercise promotes the release of insulin-like growth factor-1 and its downstream targets, growth hormone and brain-derived neurotrophic factor, to drive muscle and neuron growth. Sauna use increases these factors, too, and when used post-exercise, may have a synergistic effect to improve cardiovascular, musculoskeletal, and neurological health.”

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“In a placebo-controlled study of eight healthy adults, adrenaline infusion lowered plasma magnesium, and levels had not recovered one hour later. Investigators proposed a shift into cells after beta-adrenergic stimulation; the study did not measure cortisol, urinary loss, total-body depletion, or clinical deficiency.”

“The menus were matched for presented calories, energy density, total sugar, sodium, and fiber, but not added sugar: much more of the ultra-processed diet's sugar was added rather than contained in fruit. Protein was also only approximately matched, at about 14% versus 15.6% of calories.”