• Episodes
  • Topics
  • AMA
  • Science Digest
  • The Aliquot
  • Genetics
Sign in Become a member
Search
Back to episode

FoundMyFitness library

Related Episodes for The link between sirtuins, calorie restriction, fasting, and the insulin pathway | David Sinclair

Ranked by shared topics, with one result from each original episode.

191
Clip
Clip

How GLP-1 Drugs Support Weight Loss and Their Tradeoffs

May 9, 2024

“Dr. Patrick also discusses STEP 5, in which two years of treatment produced about 15.2 percent loss versus 2.6 percent with placebo, with the curve leveling while participants remained on treatment. Dual GIP/GLP-1 therapy can produce still larger losses in some trials.”

metabolism rhonda insulin obesity
Watch clip
192
Aliquot Premium

Q&A Mashup #3: Fasting

Aug 16, 2020

“Specific topics include autophagy, the process of recycling dysfunctional cells that is induced by fasting and fasting-mimicking drugs such as resveratrol and spermidine. Rhonda discusses the effects of fasting on Parkinson's disease and which groups of people should not fast.”

aliquot parkinson's fasting autophagy
Duration: 2h 18m 52s
193
Q&A
Q&A Premium

Q&A #19: Rhonda’s Time-Restricted Eating Window—Inflammation & Longer Fasts

Jan 9, 2021

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

rhonda vitamin d sleep vitamin c
194
Q&A
Q&A Premium

Q&A #33: Do Resveratrol and Berberine Blunt Exercise Benefits?—Plus Cardio Zones

Mar 5, 2022

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

rhonda vitamin d exercise parkinson's
195
Q&A
Q&A Premium

Q&A #55: Red Yeast Rice vs. Statins—Cholesterol, Diabetes Risk, & Supplement Contamination

Jan 15, 2024

Dr. Rhonda Patrick explores iodine supplementation, choline & TMAO, curcumin safety, and red yeast rice in her latest Q&A.

rhonda curcumin resveratrol sulforaphane
196
Q&A
Q&A Premium

Q&A #6: Fasting, Omega-3s, & Continuous Glucose Monitoring

Dec 6, 2019

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

rhonda vitamin d exercise sleep
197
Episode
Episode

Is Resveratrol a Longevity Compound?

Dec 30, 2019

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

resveratrol nutrition exercise brain
Play episode
198
Episode
Episode

Sleep loss impairs glucose regulation (but exercise helps)

Mar 13, 2019

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

sleep exercise obesity metabolism
Play episode
199
Clip
Clip

What Alpha-Lipoic Acid Does in Metabolism

Jan 22, 2025

“Human trials suggest that alpha-lipoic acid can modestly improve selected lipid measures. A dose-response meta-analysis of 12 studies found reductions in total cholesterol, LDL cholesterol, and triglycerides across doses from 300 to 1,200 milligrams per day.”

supplements metabolism cholesterol mitochondria
Watch clip
200
Clip
Clip

How Supplements Affect Mitochondrial Energy Production

Sep 7, 2026

“In contrast, a five-week trial in 181 people with diabetic polyneuropathy found that oral alpha-lipoic acid improved symptom scores, with more nausea, vomiting, and vertigo at higher doses. PQQ has a much smaller human evidence base.”

metabolism omega-3 mitochondria rhonda
Watch clip
Load more related episodes

Explore More

  • Home
  • Episodes
  • Membership
  • The Aliquot
  • About
  • Healthspan Gear
  • Genetics

Our Mission

Promoting strategies to increase healthspan, well-being, cognitive and physical performance through deeper understandings of biology. Learn more about Dr. Rhonda Patrick.

Questions?

Send us a message here

Search

Follow us here

  • Instagram
  • Twitter
  • Facebook

Watch and listen

  • YouTube
  • Apple Podcasts
  • Spotify
This site is protected by reCAPTCHA and is subject to the Google Privacy Policy and Terms of Service, as well as our own Privacy Policy and Terms of Service.