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Related Episodes for Telomeres explained: role in genomic stability, stem cells, replicative senescence | Elissa Epel

Ranked by shared topics, with one result from each original episode.

71
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Aliquot #9: Sulforaphane: Discovery, research, and health effects

Nov 5, 2020

“Sulforaphane switches on mechanisms that protect against cancer and other environmental insults. Sulforaphane is produced when the plants' cells are damaged by chewin or chopping and some culinary "hacks" favor its production.”

aliquot cancer environment sulforaphane
Duration: 36m 12s
72
Aliquot Premium

Aliquot #90: Inflammation and the Early Seeds of Dementia — and Its Prevention

Jun 4, 2023

“Preventing dementia requires a lifelong and multipronged approach that involves keeping inflammation (and its aging effects) at bay and making healthy lifestyle choices, such as exercising and consuming omega-3 fatty acids.”

aliquot exercise brain aging
Duration: 21m 40s
73
Aliquot Premium

Aliquot #96: Thermal Stress, Part I: The Science Behind Heat Stress and its Positive Effects on Health

Oct 22, 2023

Hormesis is a compensatory defense response to a stressor that conditions the body against future stressors. Heat exposure – from sauna use, hot tubs, or eve...

aliquot aging metabolism heat stress
Duration: 43m
74
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Accelerating Alzheimer's detection with biomarkers | Axel Montagne, Ph.D.

Mar 25, 2023

“Early biomarkers of vascular dysfunction, such as soluble platelet-derived growth factor receptor-beta (sPDGFR-β), can help identify individuals at risk for developing Alzheimer's disease. These biomarkers are being validated on high-throughput platforms for large-scale testing.”

brain alzheimer's aging
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Anti-cancer effects of ketones | Dominic D'Agostino

May 26, 2020

“Researchers in Dr. D'Agostino's laboratory observed a decreased tumor burden and enhanced survival in animals that were provided a ketone supplement, even if they were fed a high-carbohydrate diet.”

ketosis cancer
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Anti-catabolic effects of heat | Dr. Stuart Phillips

Jul 10, 2022

“The mechanisms that drive the effects of sauna bathing include activation of heat shock proteins and pro- and anti-inflammatory cytokines; decreased blood pressure and arterial stiffness; and multiple improvements in cardiovascular function.”

muscle exercise aging heat stress
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APOE 3/4 and APOB and their influence on Alzheimer’s and cardiovascular disease | Peter Attia

Feb 11, 2020

“Approximately 25 percent of people living in the United States carry a genetic variant of this lipoprotein called APOE4, which is associated with higher circulating levels of LDL cholesterol and an increased risk for Alzheimer's disease.”

alzheimer's brain aging cardiovascular
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78
Episode
Episode

Dr. Aubrey de Grey and Dr. Rhonda Patrick Talk Aging

Aug 13, 2015

“Dr. Aubrey de Grey is a biomedical gerontologist and the founder of the SENS Research Foundation which aims to find technologies that can repair the various types of damage that occur during the aging process. Learn more about Dr. Aubrey De Grey SENS Research Foundation.”

aging obesity dna damage stem cells
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Autophagy and cancer: a crucial role in immunosurveillance and chemotherapeutic treatment

Jul 15, 2019

“Activation of this important system of immunosurveillance is a predictor of the long-term efficacy of chemotherapy and may help to explain the complex relationship of autophagy with cancer, wherein the initial suppression of autophagy may help prevent attracting undue attention from the immune system, but may later facilitate ongoing transformation.”

autophagy cancer immune system
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B-Hydroxybutyrate protects against oxidative stress as a nutrient and as a transcription regulator | Eric Verdin

Jul 15, 2019

“Researchers have determined that beta-hydroxybutyrate is an endogenous regulator of HDACs and is able to regulate age-related genes such as FOXO3. In this clip, Dr. Eric Verdin discusses the role of beta-hydroxybutyrate in protecting against oxidative stress, both as a nutrient, but also as a transcription regulator.”

aging ketosis fasting
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