Ranked by shared topics, with one result from each original episode.
“In this Aliquot, Drs. Satchin Panda, Andrew Huberman, Layne Norton, Brad Schoenfeld, Martin Gibala, and I examine how circadian biology, training intensity, and life schedule shape exercise timing. We also explore what that means for deciding when to train.”
“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”
“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”
“Modulating autophagy – through fasting and exercise (which both increase acetyl CoA) or intake of nutrients like spermidine – represents a promising therapeutic approach for extending human lifespan and healthspan.”
“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”
“A more useful approach is to focus on what you can do to reduce its effects. In this Aliquot, Dr. Kelly Starrett explains why standing more is not enough, how to build movement into your workday, and why it matters for long-term mobility.”
“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”
“Coordination of meal timing with the circadian rhythm can reduce markers of inflammation and affect aspects of metabolic health, including glucose regulation and insulin sensitivity. Animal studies suggest that overnight fasting induces autophagy.”
“Insulin-like growth factor-1, or IGF-1 for short, is a protein that plays critical roles in major growth pathways in the human body. It influences nearly every tissue in the body, especially developmental growth, skeletal muscle and neurons.”
“As for this last point in particular, but also all conversations surrounding severe life-altering diagnosis like cancer, these clips are not meant to serve as a substitute for medical advice.”