Related Episodes for Time-restricted eating may help sleep, metabolism, and spontaneous activity (apart from weight loss) | Ruth Patterson

“Some of the factors contributing to these variable phenotypes include persistent damage to our DNA and mitochondrial dysfunction, driven by an altered NAD:NADH ratio, the latter of which has recently been shown to be improved by certain dietary supplements like nicotinamide riboside.”

Dr. Kelly Starrett joins Dr. Rhonda Patrick to discuss building a durable body, reclaiming lost mobility, and raising more resilient young athletes.

“The clip also raises questions about micronutrient status. A systematic review found a slight association between vitamin D status and total testosterone, with substantial heterogeneity, and concluded that both may reflect overall health status.”

“In this brief episode, we learn how restoring our dietary and sleep pattern to one that more closely syncs with those imposed by nature, especially by avoiding eating within 2-3 hours before bed and onset of melatonin production, may improve our health and potentially prolong our healthspan.”

“The good news is that extending sleep by ~1 hour per night has been shown to improve insulin sensitivity, normalize levels of appetite-regulating hormones, reduce cravings for sweet and salty foods, decrease sugar consumption, lower caloric intake, and aid in weight loss.”

“People who have narcolepsy, a chronic neurological disorder, experience very irregular sleep-wake cycles and may fall asleep during routine daily activities such as driving or troubleshooting a difficult problem.”

“Dr. Patrick therefore favors lower-risk tools for focus, including high-quality sleep, exercise, cocoa flavanols, deliberate cold exposure, and modest caffeine, before considering an addictive stimulant. Nicotine is not equivalent to tobacco smoke, but that does not make chronic use benign.”

“Conversely, animal studies suggest that caloric restriction may slow epigenetic aging. In this clip, Dr. Steve Horvath describes research suggesting that caloric restriction in animals, although it is unclear this will translate to humans.”

Dr. Levine shares personal habits she has developed to slow aging, including exercise, a plant-based diet, and time-restricted eating.

“Hospitalization and an overnight fast can create long periods without amino acids, especially when breakfast is low in protein, so a protein-rich breakfast creates an early opportunity to stimulate muscle protein synthesis.”