Related Episodes for What causes Alzheimer's disease? | Dale Bredesen & Rhonda Patrick

“Dr. Panda discusses the effects of time-restricted feeding on systemic inflammation; time-restricted eating as an opportunity for night-time repair that may prevent intestinal hyperpermeability (i.e., leaky gut), a primary source of systemic inflammation; and how the timing of macronutrients may differentially affect gut permeability.”

“Older adults can have anabolic resistance and may need more protein per meal to reach a leucine threshold; Dr. Schoenfeld discusses roughly 2–3 grams of leucine as a flexible estimate, not a hard cutoff or a reason everyone needs isolated leucine.”

“The trial found selected changes in antioxidant capacity, immune-cell apoptosis, and inflammatory gene expression, while several main circulating oxidative-stress measures did not differ from plain water. Clinical findings remain modest and depend on the population and outcome.”

“Peak plasma flavan-3-ol metabolites after the banana smoothie were 84 percent lower than after the capsule, while the low-PPO berry smoothie produced levels similar to the capsule. PPO is released when plant tissue is cut, bruised, or blended and can react with selected polyphenols before they reach circulation.”

“Longer endurance aerobic exercise seems to be most effective at producing higher levels of FGF21, coinciding with anecdotes you might have heard from runners who have successfully used exercise in this sort of way. Relevant publications Flippo, Kyle H., et al.”

“A meta-analysis of 49 resistance-training studies found small additional gains from protein supplementation, with fat-free-mass gains leveling near 1.6 grams per kilogram per day in the studied populations.”