Search results for depression

“"In a study involving more than 400 older adults, those randomized to intervention programs involving exercise or problem-solving strategies experienced an average of 115 more depression-free days per year than those who received the typical care.". Physical activity Several observational studies have found that physically active people are less likely to develop depression.”

“Individuals experiencing depression typically show an unfavorable shift—characterized by elevated ratios of kynurenine to tryptophan and increased quinolinic acid levels. Conversely, experimental studies in animal models demonstrate that enhancing KAT enzyme activity offers protection against stress-induced depression.”

“Relevant publications Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo. Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial (2016).”

“Acute activation of the immune system (from exercise or sauna use for example) can temporarily reduce inflammation and the depression that can come with it. The segments brought to you by this episode of The Aliquot feature professor of psychiatry Dr. Charles Raison.”

“This episode dives into a very important topic: the involvement of the immune system, especially chronic elevation of it, in depression. Chronically elevated inflammation is increasingly being shown by emerging research as having a relationship with depression.”

“Available pharmaceutical treatments have their advantages and disadvantages, and while they are helpful for a subset of depressed people, a quarter of patients taking antidepressants may get worse. In this clip, Dr. Charles Raison discusses his belief that ancient practices encourage resilience and stave off depression.”

“Randomized controlled trials have also demonstrated that exercise may be an effective intervention for preventing or mitigating depression, especially as an adjunct treatment. Perhaps some of the most interesting findings come from mechanistic studies, which have identified the molecular mechanisms that drive the improvements in mood that accompany exercise.”

“Inflammation is an important aspect of immunity. Robust evidence indicates that increased inflammation is linked with depression. Some scientists think that depression in humans may have evolved along with sickness because the two conditions have several symptoms in common.”

“Heat stress as a means to sensitize pathways important to thermoregulatory cooling that also affect brain regions implicated in the regulation of mood. The thermoregulatory dysregulation found in other relevant psychiatric conditions outside of depression, such as schizophrenia.”

“They'll combine cognitive behavioral therapy with sauna use and measure inflammatory biomarkers (which are often elevated in people who have depression) to gauge the intervention's effects. Ultimately, Dr. Mason's goal is to identify sustainable, implementable strategies that help maintain wellness and help reduce symptoms of depression.”