Search results for genome

“Jennifer Doudna, Ph.D. - Nobel Prize-winning biochemist and co-developer of CRISPR-Cas9, mentioned in connection with new genome-editing tools. Andrej Karpathy, Ph.D. - AI researcher referenced for a personal wiki/database workflow that can preserve long-term context for AI systems.”

“The body's ability to generate nitric oxide, a molecule involved in keeping blood pressure under control, falls with age, but providing oral microbes with nitrate-rich foods may help to compensate for this decline by generating more of its precursor, nitrite.”

“In the first experiment, the researchers used transgenic mice whose genomes had been altered to express the human sex hormone-binding globulin gene. They fed these mice a diet high in either sucrose, glucose, or fructose (three types of simple sugars) for one week and measured blood levels of sex hormone-binding globulin.”

“Most people living in the United States only get about half of the recommended amounts of fiber daily. The study involved nearly 3,900 adults (average age, 63 years) who had chronic kidney disease and were enrolled in the Korean Genome and Epidemiology Study.”

“The authors conducted a genome-wide association study, a type of study in which researchers look for associations between gene variations called single-nucleotide polymorphisms and disease prevalence.”

“00:05:47 - The genome-protective function of the telomere caps found at the end of our chromosomes, - special focus of Dr. Epel's - which makes telomere function an important tie-in for both the biology of aging and the biology of stress tolerance.”

“Over 15% of the human encoding genome is regulated by the sleep-wake cycle! Everything from metabolism, the immune system, and brain function depend on sleep. You don't want to miss this video interview, loaded with extra, helpful annotations.”

“*DNA methylation age of human tissues and cell types - 2013 Genome Biology paper behind the original multi-tissue Horvath clock. *DNA methylation-based biomarkers and the epigenetic clock theory of ageing - Horvath and Kenneth Raj review; useful for the "what are these clocks measuring?"”

“Scientists are exploring a wide range of cutting-edge therapies aimed at understanding and manipulating the complex processes underlying these hallmarks, including epigenetic aging clocks and pluripotent stem cells.”

“Satchin's work deals specifically with the timing of food and its relationship with our biological clocks, which are governed by a circadian rhythm. "Mice that ate within a 12-hour time period had 70% less fat and 28% less total body mass.".”