Search results for mitochondria

“To look for functional mitochondrial effects, Dr. Attia uses controlled Zone 2 work while sampling lactate, with output near 2 mmol/L. He says statins have not produced the clear lactate-performance changes he sees with metformin.”

“The body has elegant mechanisms that allow it to utilize non-carbohydrate substrates to generate glucose. Gluconeogenesis is a metabolic pathway in which the liver produces glucose from non-carbohydrate substrates including glucogenic amino acids (from protein) and glycerol (from lipids).”

“In addition, exercise preferentially causes the brain to take up lactate. Dr. Attia discusses some interesting research from several decades ago that uncovered the shifts in metabolism that occur in the human body and brain upon extreme fasting.”

“A common feature of heart disease is arrhythmia, an irregular heartbeat. Interestingly, research in fruit flies has shown that unhealthy lifestyle behaviors, such as poor sleep and diet, increase the risk of developing arrhythmias.”

“As we age, our hair changes: It often turns gray and becomes finer, and it might even fall out—permanently. There are seemingly millions of hair care products available, and many of them contain chemicals that may harm our hair or, even worse, harm our health. In this Aliquot, I explore the various ways to prevent hair loss and promote healthy hair.”

“In this clip, Drs. Levine and Patrick discuss the epigenetic changes that occur with age, including methylation of CpG sites. Using methods discovered in recent research, the program of cellular aging may be reversible without disrupting cell function.”

“Researchers have observed synergism between the ketogenic diet and hyperbaric oxygen against tumor cells. Moreover, Dr. D'Agostino suggests that ketosis stimulates the immune system, increasing its ability to detect cancer cells.”

“In this clip, Drs. Levine and Patrick discuss new advances in cellular aging research that show it's possible to reverse aging and generate new stem cells from already differentiated cells. Dr. Levine also discusses parabiosis, a treatment that involves giving old mice an infusion of plasma from young mice, and how it may reverse the cellular changes that accumulate during aging.”

“The benefits of HIIT include improvements in muscle tissue oxidative capacity, enhanced insulin response, improvements in heart function, and increased lactate – an important source of fuel for the heart, brain, and muscles.”

“In this 45-minute podcast, Dr. Patrick answers some of the most popular questions related to fasting, including: What effects coffee, supplements, and amino acids have on fasting. Whether one method of fasting is more beneficial than others.”