Search results for hypoxia

“But exogenous ketones may act to preserve performance and resilience in extreme environments, such as hypoxia. For example, there could be a rationale for using ketones to augment performance for people who are mountain climbing, running, or cycling.”

“Apnea interferes with deep sleep, induces hypoxia, and promotes amyloid-beta accumulation in the brain. In this clip, Dr. Matthew Walker describes the dual risk of carrying the APOE4 allele and having sleep apnea.”

“Repeated breathing interruptions fragment sleep and create cycles of falling and recovering oxygen levels throughout the night. Intermittent hypoxia and sleep fragmentation can increase oxidative stress, inflammation, and cognitive strain.”

“Furthermore, vitamin C is an important compound needed for the regulation of hypoxia-inducible factor 1-alpha, or HIF 1-alpha, a transcription factor that has been implicated in the pathogenesis of cancer and other diseases.”

“Subsequently, proteins, fats, carbohydrates, and nucleic acids are released for energy and re-use. The process of autophagy is activated by cellular stressors such as nutrient depletion, hypoxia, and the presence of toxins.”

“During exposure to temperature extremes or hypoxia (low oxygen levels), cells increase their expression of heat shock proteins to stabilize unfolded proteins and repair damaged ones. This phenomenon, referred to as the heat shock response, occurs at the expense of other cellular proteins to protect the cell.”

“Hyperbaric (i.e., high air pressure) treatments use increased atmospheric pressure and oxygen content to enhance the total amount of oxygen dissolved in the body, accelerating wound healing. Some forms of routine hyperbaric therapy cause the body to react as if it were experiencing hypoxia (i.e., low blood oxygen), a phenomenon called the hyperoxic-hypoxic paradox.”

“Disturbances in this system due to the loss of ACE2 function in the setting of SARS-CoV-2 infection can promote neutrophil infiltration, excessive inflammation, and lung injury. Once lung infection progresses to hypoxia, renin is released, setting up a vicious cycle for decreasing ACE2.”

“> [New research] shows that adult offspring from pregnancies complicated by chronic hypoxia have increased indicators of cardiovascular disease, such as high blood pressure and stiffer blood vessels. [...]”

“They found that bright light triggered the activity of PER2, a gene that regulates the body's circadian rhythms. Activating PER2 protected against hypoxia – a condition in which low oxygen levels (caused by reduced blood flow) can damage the heart.”