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“Exercise activates pathways that are involved in maintaining connections between neurons, making them stronger and repairing damage. In this clip, Dr. Giselle Petzinger describes how exercise may provide a repair model that allows some type of resilience against the insults of Parkinson's disease.”

“A meta-analysis showed that men and women achieved similar increases in muscle with resistance training, despite men having higher testosterone levels. While daily fluctuations in testosterone do not drive muscle protein synthesis, supraphysiological steroid doses are anabolic.”

“Dr. Roland Griffiths is a clinical pharmacologist at Johns Hopkins and one of the world's foremost researchers on the psychedelic compound psilocybin. Learn more about Dr. Roland R. Griffiths Johns Hopkins Profile - Roland R. Griffiths. List of Publications.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“Consuming sufficient protein is essential for muscle growth and maintenance. Emphasis on specific amino acids within protein, particularly the branched-chain amino acids, probably isn't necessary unless you're an elite athlete or an older adult.”

“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”

“Beyond its role in sexual development, testosterone is important for overall health, influencing mood, energy levels, and even cognitive function. Testosterone is also a highly contested topic, especially in the context of resistance exercise, lifestyle, and managing low testosterone.”

“In this Aliquot, I'm joined by exercise-oncology researcher Dr. Kerry Courneya to identify and prioritize the lifestyle behaviors that account for much of the difference in cancer risk and have the greatest long-term impact.”

Dr. Rhonda Patrick discusses protein needs, choline in pregnancy, urolithin A, melatonin's benefits and risks, and creatine's effects on liver health.

“But with their rise in popularity come important questions about long-term effects and safe use. In this Aliquot, I discuss how these drugs work, their pros and cons, the latest research, and lifestyle strategies to optimize their effects for long-term health.”