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“In this Aliquot, I'm joined by Drs. Martin Gibala, Luc van Loon, and Brad Schoenfeld to break down how to manage load, train in joint-friendly ways, reduce inflammation, and separate supplements supported by evidence from those that remain uncertain.”

“Lifestyle factors, such as exercise, nutrition, sleep, and others, can temper some of the risks associated with carrying APOE4. This Aliquot focuses on the ones that can have the greatest benefits – and the ones that do the most harm.”

“While exercise and caloric restriction have the potential to slow aging, rejuvenation has the potential to repair the damages associated with aging once they have occurred. In this clip, Dr. Eric Verdin explains how exercise and nutrition form the cornerstone of strategies to slow aging, but exciting approaches lie ahead.”

“Dr. Patrick also revises an earlier concern about acrylamide: although roasting can form it, the human evidence she reviews does not show that ordinary coffee intake raises cancer risk, and the overall epidemiology points in the opposite direction for several cancers.”

“Epigenetic clocks may provide a means of explaining these and other differential aging rates. In this clip, Dr. Steve Horvath discusses how traditional biomarkers of health and age don't correlate well with epigenetic age.”

“Additionally, we also discuss the important role magnesium plays in preventing random mutations. "Men with the highest quartile of magnesium levels have a 40% decrease in all-cause mortality and a 50% decrease in deaths from cancer.".”

“Late-night eating can have negative effects on our health. But time-restricted eating limits the daytime window during which a person eats to take advantage of the time when metabolism is optimized, improving health and even promoting weight loss.”

“However, combining fasting with resistance training can stimulate muscle growth. In this Aliquot, Dr. Rhonda Patrick discusses time-restricted eating, fasting, and muscle preservation, highlighting key differences and offering recommendations for specific groups.”

“In the modern-day with no imposed fasting, these cycles of renewal may remain dormant. In this clip, Dr. Valter Longo discusses how cellular repair mechanisms may have evolved during times of fasting, but are latent in times of food abundance.”

“In this Aliquot, cardiologist Ben Levine, nutritional scientist and champion powerlifter Layne Norton, and I discuss the importance of recovery, how best to approach it, and some surprising, often overlooked aspects of this important part of fitness.”