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Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick discusses urolithin A, postmenopausal protein, microplastics, high-temperature saunas, sugar intake, and supplements for Parkinson's disease.

“However, the ability to translate data from non-human animals to humans can be limited and the use of laboratory animals can raise ethical concerns. In this clip, Dr. George Church describes the pros and cons of animal research and how we could move beyond its use with advanced technologies.”

“Autophagy is a cellular defense mechanism that gathers protein aggregates, pathogens, and damaged or dysfunctional organelles into vesicles within the cell and then delivers them for destruction. Subsequently, proteins, fats, carbohydrates, and nucleic acids are released for energy and re-use.”

“Biotechnology may have a special potential to create change across generations, as it has done with the global eradication of smallpox – a vaccine that ceased mainstream use in the 1970s. Synthetic biology, with its potential to eradicate viral illnesses, could usher in an era of global progress.”

“The idea of a smart phone that is able to replicate itself sounds like science fiction in our current age, but technologies like this could be on the horizon with advanced genetic technologies.”

“Poor sleep reduces the body's insulin sensitivity and changes a person's appetite, increasing the preference for high carbohydrate foods like pizza, pasta, and sweets. Lack of sleep also alters the gut microbiota and impairs immunity, putting us at risk for developing acute illnesses like colds and flu.”

“Three of the most common human diseases are cardiovascular disease, cancer, and Alzheimer's disease. The most significant drivers of cardiac disease are smoking, hypertension and elevated APOB, a biomarker of LDL particle number.”

“Osimertinib, for example, improved five-year survival among patients with resected EGFR-mutated lung cancer, while CAR-T therapy has produced durable remissions in some children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia.”

“A preliminary study shows atrophy in olfactory brain regions and areas responsible for learning and memory, after COVID-19 illness, even in those with mild cases. Converging evidence suggests that the long-term impacts of SARS-CoV-2 infection are unknown.”