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Urolithin A is a gut-microbe-derived metabolite formed from ellagitannins or ellagic acid in foods including pomegranates, berries, and walnuts. Its main area of interest is mitochondrial quality control, particularly mitophagy—the cellular clearance of damaged mitochondria. Because…

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Urolithin A

Jul 11, 2026

“At rest, one signaling molecule (IL-2) was slightly lower, and there was no broad increase in inflammatory cytokines. The immune system wasn't more inflamed at baseline after urolithin A supplementation, but it was more primed to respond.”

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Aliquot #150: Can Urolithin A Renew Aging Mitochondria?

Aug 28, 2026

“Urolithin A is a compound produced by certain gut bacteria from polyphenols found in foods like pomegranates, berries, and walnuts. It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria.”

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