A high dose of fish oil (4g/day) lowered triglyceride levels by 20-30% in people with high triglycerides.
“However, when the drug is given to people with very high triglyceride levels at 500 mg/dL or greater, LDL-C may increase. •The panel's review found that prescription omega-3 fish oil is effective in reducing triglyceride levels regardless of whether people are on statin therapy.”