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“Dr. Rhonda Patrick visits the Kevin Rose Show to discuss metformin, magnesium L-threonate, fish oil and brain health, sulforaphane, goitrogenic activity of isothiocyanates, sauna, and more. Subscribe to the Kevin Rose Show on iTunes. Learn more about Kevin Rose @kevinrose on Twitter. KevinRose.com. The Kevin Rose Show on iTunes. Foundation by True Ventures.”

“- Dr. Mark Mattson https://www.foundmyfitness.com/episodes/mark-mattson/'] Whether we induce energetic crises through fasting, exercising, or tapping into a subset of the body's metabolic program through a specialized diet, some of the more compelling entities that define the ensuing metabolic switch are ketone bodies.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“In Dr. Raison’s randomized, double-blind study published in JAMA in 2016, it was shown that a single session of whole-body hyperthermia (core body temperature was elevated to 38.5 C) produced a significant antidepressant effect in people with major depressive disorder compared to those who received a sham control.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“00:29:20 - Organs shrink during fasting and then regrow after refeeding. Study. 00:29:45 - Fasting stresses healthy cells so they increase their stress-response pathways, including heat shock proteins, antioxidant production, and anti-inflammatory.”

“"Although those other lifestyle choices play a role, this study unequivocally demonstrates that visceral adiposity is causally linked to intestinal cancer." There was a sex-specific effect: > The researchers then subdivided the groups by gender.”

“Results showed that processing level, not just calories, shaped health outcomes: Men gained about 1.3 to 1.4 kilograms more (mostly from increased fat mass) on the ultra-processed diet than on the minimally processed diet, in both the adequate- and excess-calorie groups.”

Tim Ferriss discusses ketosis, the gut microbiome, and monitoring biomarkers to promote performance.

“Dr. Candow explains why a hormone change within the physiological range cannot by itself establish a hair effect. A later 12-week randomized trial directly measured hormones and hair-follicle outcomes in resistance-trained men taking five grams of creatine per day.”