Search results for aging

“In addition, the epigenetic clock assesses changes in DNA methylation that are predictive of age. In this clip, Dr. Eric Verdin describes the emerging field of biomarkers of aging and the diverse strategies, including artificial intellegence, that are being employed.”

“These changes increase infection risk, weaken vaccine responses, and reduce early cancer surveillance. Yet immune aging is not fixed. Movement, sleep, stress regulation, temperature exposure, and nutrition shape immune cell balance and inflammatory activity over time.”

“*DNA methylation GrimAge strongly predicts lifespan and healthspan - GrimAge paper from Ake Lu, Steve Horvath, and collaborators; key background for the episode's mortality-risk caveats. *DunedinPACE, a DNA methylation biomarker of the pace of aging - useful for the pace-of-aging / "speedometer" discussion.”

“In this clip, Drs. Levine and Patrick discuss definitions of aging used in science and why biological aging matters to scientists. Dr. Levine shares the hallmarks of aging that help researchers determine someone's biological age, what drives accelerated aging, and what epigenetic modifications such as CpG methylation say about the aging process.”

“In the five-year Generation 100 trial, adults ages 70 to 77 completed supervised high-intensity interval training or moderate continuous training, demonstrating that structured vigorous exercise can be feasible in older populations when it is introduced progressively and matched to health and fitness.”

“The progressive loss of skeletal muscle mass and strength that occurs with aging, referred to as sarcopenia, begins as early as our 30s or 40s. Many factors contribute to sarcopenia, including diet and inactivity.”

“In this clip, Drs. Patrick and Levine discuss the reliability of epigenetic age tests available to consumers. Do these tests provide accurate results, and how should we interpret them? Dr. Levine discusses the shortcomings of current epigenetic age testing for consumers and what measuring epigenetic age at one timepoint really means about true biological age.”

“Her research merges the varied genetic, environmental, and evolutionary forces that drive aging and age-related diseases, and identifies modifiable pathways that can mitigate basic aging processes. Dr. Campisi has contributed to several discoveries that continue to challenge and alter current thinking about the science of aging.”

“Listen as recent podcast guest from episode 72 of the FoundMyFitness podcast, Dr. Morgan Levine, describes the importance of this step in making her epigenetic clock PhenoAge and that of her postdoctoral mentor GrimAge more accurate in their ability to detect biological age and epigenetic age acceleration.”

“The effect on global cognition was statistically comparable with about two years less cognitive aging, supporting a role for adequate micronutrient intake alongside exercise, sleep, and cardiovascular health.”