Search results for aging

“Excess glucose is diverted to the sorbitol pathway, increasing cellular swelling that eventually causes a cell to burst. However, insulin promotes aging independent of high glucose levels through persistent and chronic mTOR activation and autophagy inhibition.”

“Telomerase, an enzyme that extends the length of telomeres, is critical to healthy cellular aging. But having too much telomerase – as in the case of cancer cells – can be a bad thing. Cancer cells exploit the regenerative capacity of telomerase to perpetually divide, essentially becoming immortal.”

“In addition, a father's age at conception influences sperm telomere length and subsequently the telomere length of his children. New research will focus on determining whether telomere length at birth predicts both lifespan and healthspan.”

“Emerging evidence suggests that IGF-1 also regulates the aging process via its influence on growth hormone. In this clip, Dr. Valter Longo describes the IGF-1 pathway and explains how defects in the pathway influence disease risk.”

“In Part II of this three-part series, Dr. Candow and I will cover the incredible brain benefits of creatine, especially in the settings of stress, aging, trauma, neurodegenerative disease, and more.”

“Bruce explains that this may still leave people insufficient for long-term diseases. In light of his triage theory, this means a poor diet may have enough nutrition to prevent serious acute diseases but still lead to accelerated aging and long-term diseases.”

“Most common graying is strongly related to age and genetics, but selected observations suggest that stress, nutrient status, and cellular energy metabolism can influence pigment in some circumstances.”

“Part I of this three-part Aliquot segment features Dr. Dale Bredesen, an expert in Alzheimer's disease; Dr. Dominic D'Agostino, an expert in ketosis; and Dr. Peter Attia, a medical doctor specializing in aging.”

“Stress, pathology, and aging can alter brain energy metabolism. During times of impaired brain energy, the brain may prefer to use ketones as a fuel source. The use of alternate fuel sources allows glucose to be spared for the metabolic pathways that require it.”

“By the age of six months, however, infants can develop iron-deficiency anemia, so introducing iron-rich foods in addition to breast milk is recommended. In this clip, Dr. Rhonda Patrick explains why iron levels in breast milk are low.”