Search results for apoptosis

“When the telomeres on a cell's chromosomes get too short, the chromosome reaches a "critical length," and the cell enters senescence or undergoes apoptosis. Telomere length is measured in base pairs – the coupled building block units that make up the ladder-like rungs of our DNA.”

“(Pro-)thrombin - A neurotoxic clotting protein that activates microglia by upregulating pro-inflammatory pathways, such as NF-kB, and promoting further blood-brain barrier degradation and neuronal apoptosis.”

“These remarkable and diverse molecules reduce the inflammation that drives many chronic diseases, promote apoptosis, regulate leukocyte (white blood cell) activity, and reduce the production of proinflammatory mediators.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“CTCs have mechanosensors that respond to mechanical forces, and during vigorous exercise, high blood flow and shear stress can push these fragile cells over the edge, triggering a form of programmed cell death called apoptosis.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“AGEs are potentially harmful molecules derived from the nonenzymatic glycation of proteins—they promote oxidative stress, inflammation, and apoptosis. High glucose also promotes aging through another pathway. When cells are overwhelmed with glucose, they can't break it down effectively.”

“In the modern-day with no imposed fasting, these cycles of renewal may remain dormant. In this clip, Dr. Valter Longo discusses how cellular repair mechanisms may have evolved during times of fasting, but are latent in times of food abundance.”

“Whereas fasting turns off multiple pathways associated with aging, such as mTOR and IGF-1, eating for optimal fitness activates these important processes. The IGF-1 pathway, in particular, plays key roles in growth and is strongly associated with cancer.”