Search results for oxidative stress

“Oxidative stress arises when excess reactive oxygen species overwhelm the body's capacity to mount an effective antioxidant response.”

“01:16:35 - Protective mechanisms, such as the activation of tumor suppressor genes, are induced by hormesis – a type of protective stress response triggered by things like isothiocyanates. 01:20:20 - Plants produce toxic compounds that have a net positive effect because they induce hormesis.”

“When administered intravenously, the vitamin C dose is so high that it forms the oxidized form and this does a couple of important things that can kill cancer cells. First, it causes oxidative stress in cancer cells (a well known mechanism to activate cell death of a cancer cell).”

“This study shows some pretty interesting things in terms of a dramatic ability to (apparently) decrease lead status in the blood and seems to also really improve memory performance and reduce oxidative stress (from the lead) in the brain.”

“There are a couple of mechanisms by which acetaminophen has been speculated to alter fetal brain development including acting on cannabinoid receptors, which help determine how neurons mature and connect with one another, altering the immune system, or by increasing oxidative stress.”

“Whereas average blood vitamin C levels among the healthy controls were 56 micromoles per liter, levels among the patients with pneumonia were 23 micromoles per liter. The pneumonia patients also exhibited elevated protein carbonyl concentrations compared with the healthy controls, indicating enhanced oxidative stress.”

“Sulforaphane is a potent antioxidant and anti-inflammatory compound Prominent features in the pathogenesis of many chronic diseases are oxidative stress and inflammation. Oxidative stress is a natural repercussion of normal metabolic processes during oxidative phosphorylation (the generation of energy) in mitochondria or accompanying hypochlorite generation during immune activation.”

“Spermidine supplementation suppressed senescence in epithelial cells in mice when challenged with bleomycin, which causes oxidative stress. Navitoclax increased clearance of senescent chondrocytes in an in vitro model of osteoarthritis.”

“Several mechanisms explain why, minute for minute, vigorous exercise outperforms moderate- and light-intensity activity for achieving several heath benefits. Shear Stress and Endothelial Function Vigorous exercise dramatically increases blood flow and shear stress—the friction of blood sliding along the inner surface of blood vessels.”

“Protecting DNA and RNA from cytotoxic stimuli like oxidative stress: Creatine has been shown to protect against mitochondrial DNA damage and mutagenesis from UV radiation. It also shows potential for protecting against RNA damage.”