Related Episodes for Day–night patterns of light exposure

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

Dr. Kelly Starrett joins Dr. Rhonda Patrick to discuss building a durable body, reclaiming lost mobility, and raising more resilient young athletes.

“Dr. Patrick also discusses glucose, HbA1c, fasting insulin, kidney and electrolyte markers, hs-CRP, fibrinogen, thyroid tests, CBC, vitamin D, sex hormones, IGF-1, and the Omega-3 Index.”

“In addition, exercise preferentially causes the brain to take up lactate. Dr. Attia discusses some interesting research from several decades ago that uncovered the shifts in metabolism that occur in the human body and brain upon extreme fasting.”

“I am simply saying you would be even more healthy if you also included fiber...if you also included fruits and vegetables.” - Layne Norton, Ph.D. The Carnivore Diet Eating an all meat or all animal product diet—commonly referred to as the carnivore diet—has been hailed by many as the only diet that’s provided a cure for their autoimmune disease or other health issues.”

“The clip also raises questions about micronutrient status. A systematic review found a slight association between vitamin D status and total testosterone, with substantial heterogeneity, and concluded that both may reflect overall health status.”

“People who have poor cardiorespiratory fitness are more likely to be depressed. Sauna improves cardiorespiratory fitness and may offer a means to ameliorate the symptoms of depression and improve mood. In this clip, Drs. Rhonda Patrick and Jari Laukkanen discuss the benefits of sauna use in terms of cardiorespiratory fitness and mood.”

“The mast cells release pro­inflammatory cytokines and proteases that damage the gut, leading to intestinal permeability, a condition otherwise known as “leaky gut.” This leakiness allows bacteria and bacterial antigens to cross the gut’s inner layer, the epithelium, and activate even more immune cells, leading to more inflammation – a key driver in the aging process.”

“Whether metformin reduces the risk of cancer in healthy people remains to be seen. In this clip, Dr. Rhonda Patrick describes the relationship between metformin and cancer incidence and the relevance for those with type 2 diabetes.”