Related Episodes for Melatonin

“00:29:20 - Organs shrink during fasting and then regrow after refeeding. Study. 00:29:45 - Fasting stresses healthy cells so they increase their stress-response pathways, including heat shock proteins, antioxidant production, and anti-inflammatory.”

“02:03:18 - A recent study measured omega-3 fatty acid levels from both supplemental and dietary sources in blood and found that for every 1 percent increment in omega-3 fatty acid levels there was a 20 percent decreased risk in all-cause mortality.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

Dr. Kelly Starrett joins Dr. Rhonda Patrick to discuss building a durable body, reclaiming lost mobility, and raising more resilient young athletes.

“Ketone esters are exogenous ketone bodies that may promote ketosis in humans. Animal models demonstrate that ketone esters exert beneficial effects in Alzheimer's disease, effectively reducing amyloid accumulation, neurofibrillary tangles, and tau, while improving learning and memory.”

“The clip also raises questions about micronutrient status. A systematic review found a slight association between vitamin D status and total testosterone, with substantial heterogeneity, and concluded that both may reflect overall health status.”

“The good news is that extending sleep by ~1 hour per night has been shown to improve insulin sensitivity, normalize levels of appetite-regulating hormones, reduce cravings for sweet and salty foods, decrease sugar consumption, lower caloric intake, and aid in weight loss.”

“Assessing and quantifying the exposome — all of the non-genetic tangible exposures we experience during a lifetime, including those from the air, physical surroundings, microbes, and chemicals — is challenging.”

“People who have narcolepsy, a chronic neurological disorder, experience very irregular sleep-wake cycles and may fall asleep during routine daily activities such as driving or troubleshooting a difficult problem.”

“Dr. Patrick therefore favors lower-risk tools for focus, including high-quality sleep, exercise, cocoa flavanols, deliberate cold exposure, and modest caffeine, before considering an addictive stimulant. Nicotine is not equivalent to tobacco smoke, but that does not make chronic use benign.”