Related Episodes for Sirtuins

“Ultimately, we all have to weigh the merits and the trade-offs of portable devices for ourselves and our children individually, but it might mean holding out on the tablet until they're a little older, setting rules around it, and certainly demonstrating our own self-discipline in their use.”

“Although scientists have identified other lifestyle behaviors that can help prevent the build-up of amyloid plaques by boosting the capacity for glymphatic clearance – such as exercise and adequate intake of omega-3 – the most important factor by far is a good night's sleep, especially deep sleep.”

“In a randomized trial of 80 adults with overweight who usually slept fewer than 6.5 hours, counseling increased sleep by about 1.2 hours per night and reduced objectively measured energy intake by approximately 270 calories per day over two weeks.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“Meal timing can affect selected markers in specific settings. In a five-week crossover study of eight men with prediabetes, an early six-hour window improved insulin sensitivity, beta-cell responsiveness, morning blood pressure, oxidative stress, and appetite without weight loss.”

“Since then, countless studies have tested Pauling's theories about vitamin C, colds, and cancer (and many others), and a substantial body of evidence has emerged, identifying critical roles for vitamin C in immune function, cardiovascular and respiratory health, cognitive development and preservation, and many other aspects of human health.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“Peak plasma flavan-3-ol metabolites after the banana smoothie were 84 percent lower than after the capsule, while the low-PPO berry smoothie produced levels similar to the capsule. PPO is released when plant tissue is cut, bruised, or blended and can react with selected polyphenols before they reach circulation.”

“Longer endurance aerobic exercise seems to be most effective at producing higher levels of FGF21, coinciding with anecdotes you might have heard from runners who have successfully used exercise in this sort of way. Relevant publications Flippo, Kyle H., et al.”