Ranked by shared topics, with one result from each original episode.
“Physical activity, sleep, light exposure, heat, and certain nutrients may all affect systems involved in mood regulation, including inflammation, circadian rhythms, neuroplasticity, and brain energy metabolism. In this Aliquot, Drs.”
“But exercise — especially intense exercise — can also help to manage the symptoms once the disease develops. These Aliquot segments feature Dr. Giselle Petzinger, a board-certified neurologist who specializes in the care of patients with Parkinson's disease.”
“And one potential strategy for mitigating our risk for Alzheimer's disease as we age is a "cognoscopy" – a battery of assessments that measures some of the key biomarkers associated with the disease and can inform the trajectory of treatment.”
“The decline of deep sleep begins early in life, nearly disappears by age 80, increasing the risk for Alzheimer's disease. These Aliquot segments feature Dr. Charles Raison, a professor of psychiatry, and Dr. Matthew Walker, a professor of neuroscience and psychology.”
“In the setting of COVID-19, vitamin D deficiency drives poor outcomes. Treating patients with calcifediol, a prescription vitamin D analog, might be more effective at increasing vitamin D to therapeutic levels.”
“Having a healthy, robust immune system is crucial for our survival. Critical players in the body's antiviral immune response are interferons. Certain lifestyle behaviors can boost interferon production and immune function, including sleep, vitamin D, and hot hydrotherapy.”
“Cholesterol is vital to human health, but an oversimplified view of cholesterol — that high-density lipoprotein (HDL) cholesterol is good, and low-density lipoprotein (LDL) cholesterol is bad — has led to a gross misunderstanding of the nuances that define the differences in cholesterol-containing lipoproteins.”
“Statins can reduce the risk of heart disease by 30 to 40 percent due to their ability to increase LDL receptor activity and reduce blood cholesterol levels. Whether the drugs are overprescribed (or perhaps under-prescribed) is a matter of great debate.”
“As a result, sauna use is associated with lower risk of cardiovascular and neurodegenerative diseases. The mechanisms that drive these effects are likely due to increased heat shock proteins and metabolic and hormonal changes that accompany exercise and sauna use.”
“Scientists have also identified interesting links between depression and obesity – likely mediated by elevated inflammation, since fat cells produce a wide array of inflammatory factors. In this Aliquot segment, psychiatrist Dr. Charles Raison describes the links between inflammation and depression.”