FoundMyFitness library
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“The study involved 112 women between the ages of 39 and 59 years who were assigned to take a placebo (500 milligrams of cellulose) or a commercial product (containing 300 milligrams of hydrolyzed type II collagen, 100 milligrams of chondroitin sulfate, and 50 milligrams of hyaluronic acid) twice a day for 12 weeks.”
“Creatine improves vascular health To investigate creatine's effects on blood vessel health—specifically by measuring the ability of arteries and small blood vessels to increase in size to accommodate blood flow (known as endothelial function)—one study recruited 12 healthy men and women with an average age of 59 and supplemented them with creatine or a placebo for 28 days each.”
“Neurogenesis Whereas the early view of the mammalian central nervous system presumed that it was a static complex incapable of change, a growing body of evidence suggests that it retains its capacity for synaptic pruning – the process that eliminates extra neurons and synaptic connections and establishes new neural circuits to increase the efficiency of neuronal transmissions – throughout life.”
“In laboratory tests, the redesigned factors produced more than 50-fold higher expression of stem-cell reprogramming markers than wild-type controls and generated stable induced pluripotent stem cell lines across multiple donors and delivery methods.”
“When we engage in high-intensity exercise, our muscles become mini biochemical laboratories, synthesizing compounds like lactate and myokines that circulate throughout the body and travel to our organs, where they exert a variety of signaling effects, including the synthesis of brain-derived neurotrophic factor (BDNF) in the brain.”
“Time-restricted eating exploits the body's innate 24-hour patterns – the genetically encoded molecular clocks present in every cell, from the complex (liver cells) to the simple (hair follicles) – and provides the body an essential downtime where it can focus on DNA and cellular repair and restoration rather than digestion.”
“Run the longevity report to learn more about genetic polymorphisms influencing the expression of FOXO Background FOX proteins are named for a gene found in fruit flies that causes the insects to have forked structures on their heads (providing the "F") and a particular group of specialized genes – known as a "box" (providing the "OX").”
“Multiple age-related inputs can keep innate immune pathways active, including the senescence-associated secretory phenotype, mitochondrial damage and oxidative stress, debris released by injured cells, visceral adipose tissue inflammation, chronic infections, increased intestinal permeability, and dysbiosis.”
“If you focus on eating multiple protein-containing meals each day and are thoughtful about your sources, it's likely you'll meet daily protein needs and thrive, whether your goal is gaining more muscle or just staying strong into your later years.”
“Increased intestinal permeability (also known as "leaky gut") – a condition in which gaps form between the tight junctions that join enterocytes – allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation through a specialized mechanism involving detection by toll-like receptors.”