Related Episodes for Dr. Ben Bikman: How To Reverse Insulin Resistance Through Diet, Exercise, & Sleep

“Whereas fasting turns off multiple pathways associated with aging, such as mTOR and IGF-1, eating for optimal fitness activates these important processes. The IGF-1 pathway, in particular, plays key roles in growth and is strongly associated with cancer.”

“Insulin-like growth factor 1 (IGF-1) promotes the growth of existing cancer cells and contributes to aging, but also has some beneficial functions. IGF-1 is required for the growth and repair of muscles and is also necessary for producing new brain cells.”

“Insulin-like growth factor 1 (IGF-1) plays a role during childhood for growth and continues later in life to have anabolic and neurotrophic effects. IGF-1 is also implicated in contributing to aging and enhancing the growth of cancer after it has been initiated.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“When a person does not get enough sleep, their pancreatic beta cells become less sensitive to glucose signaling, reducing the amount of insulin produced by the pancreas. This, in turn, impairs glucose uptake, resulting in hyperglycemia, a hallmark of diabetes.”

“If we eat carbohydrate-containing foods when melatonin levels are high, our pancreas cannot produce the insulin needed to use the glucose. Therefore, eating too close to bedtime or immediately upon waking, before nightly melatonin levels have declined, may hamper the body's ability to process glucose.”

Dr. Michael Snyder discusses personalized medicine and the use of technologies that monitor metabolism and other health markers.

“Dr. Patrick also discusses STEP 5, in which two years of treatment produced about 15.2 percent loss versus 2.6 percent with placebo, with the curve leveling while participants remained on treatment. Dual GIP/GLP-1 therapy can produce still larger losses in some trials.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick explores supplemental tyrosine, lion's mane, cordyceps, aging tests, and sunscreen's efficacy and safety in a Q&A.