Ranked by shared topics, with one result from each original episode.
“In this Aliquot, I'm joined by Drs. Martin Gibala, Luc van Loon, and Brad Schoenfeld to break down how to manage load, train in joint-friendly ways, reduce inflammation, and separate supplements supported by evidence from those that remain uncertain.”
“In this Aliquot, I walk through how that plays out in humans, where the strongest evidence shows up, and where it doesn't, with NAD researcher Dr. Charles Brenner—and why I'm taking it now after being skeptical.”
“Modulating autophagy – through fasting and exercise (which both increase acetyl CoA) or intake of nutrients like spermidine – represents a promising therapeutic approach for extending human lifespan and healthspan.”
“It has attracted interest for its potential to activate mitophagy, the process cells use to clear out damaged mitochondria. In this Aliquot, I explain why mitochondrial cleanup matters for aging, why urolithin A production varies, and what early human studies suggest about its potential benefits.”
“Time-restricted eating, which involves taking in food within a small window of time during the day and fasting for the remainder, can improve certain biomarkers of health – even without weight loss – to improve overall health. In Part I of this two-part segment, Drs.”
“Recent discoveries in the field of epigenetics suggest we might be able to slow aging, based on the realization that not everyone ages at the same rate. Evidence suggests that drugs or other medical procedures can slow epigenetic aging, but other factors, such as diet and disease states influence it too.”
“The decline of deep sleep begins early in life, nearly disappears by age 80, increasing the risk for Alzheimer's disease. These Aliquot segments feature Dr. Charles Raison, a professor of psychiatry, and Dr. Matthew Walker, a professor of neuroscience and psychology.”
“These changes drive processes that improve cellular respiration, reduce inflammation, enhance memory, and provide protection from cancer – critical aspects in slowing the effects of aging and promoting longevity. Part II of this three-part Aliquot features Dr. Dominic D'Agostino, an expert in ketosis; Dr. Eric Verdin, an expert in aging; and Dr. Valter Longo, an expert in gerontology.”
“The arrival of a new year is a great opportunity to make health-focused resolutions – promises to ourselves that we're going to live better, healthier, and (hopefully) longer. We all age at different rates, however, so our chronological age – the number of years we've lived – often differs from our biological age.”
“Diet stands out as low-hanging fruit for influencing our lifespan. Optimizing macronutrient intake, practicing time-restricted eating, and consuming healthful bioactive compounds are critical aspects of a healthy diet. In part II of this two-part Aliquot, Drs.”