Related Episodes for Chronotypes: Your natural propensity to be an early riser or night owl | Matthew Walker

“- Practical details like temperature and duration of sauna use, the difference between a dry, wet and infrared sauna, sauna timing, as well as other forms of heat stress such as steam showers, hot baths, and hot yoga.”

“Dr. Patrick begins with a prospective Finnish cohort in which men reporting four to seven sauna sessions per week had lower dementia and Alzheimer's disease incidence than men reporting one session. The study is observational, male-only, and cannot prove that sauna caused the lower risk.”

“Time-restricted eating, a form of fasting that limits the period during which a person eats to a 12- to 16-hour window, capitalizes on the benefits associated with both fasting and optimization of the body's circadian biology.”

“Acutely, however, caffeine can raise glucose or reduce insulin sensitivity in some people through sympathetic activation, so a short-term glucose response is not identical to the longer-term association. Timing provides the practical answer.”

“Reducing inflammation may be beneficial for a variety of physical and mental conditions. In this clip, Wim Hof shares his personal story that led to his passionate pursuit of how we can harness the body's innate ability to heal itself.”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Autophagy is an intracellular degradation system involved in the disassembly and recycling of unnecessary or dysfunctional cellular components. Fasting – even short periods of overnight fasting that occurs during time-restricted eating – induces autophagy, providing a kind of daily maintenance for the body.”

“Activity in the default mode network (DMN), a group of interacting brain regions implicated in self-related thinking, rumination, and depression, is suppressed by psilocybin and other psychedelic substances.”

“Dr. Patrick describes increased shear as a possible way vigorous exercise can damage fragile circulating tumor cells; this is a proposed mechanism, not proof that a workout eliminates metastasis or treats an established tumor.”

“However, the DNAm GrimAge epigenetic clock is a highly reliable predictor of healthspan and lifespan, based on DNAm surrogates in blood, including biomarkers of aging and alterations in blood composition.”