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“During sauna use, heart rate, and blood pressure rise, returning to below baseline levels after the session. In this clip, Dr. Rhonda Patrick describes how the physiological effects observed during sauna use are comparable to those that occur during physical exercise.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“A separate 46-year study of 5,107 middle-aged men linked each 1 milliliter per kilogram per minute increase in estimated VO2 max with about 45 additional days of life expectancy. High-intensity intervals are one practical way to improve VO2 max.”

“In a randomized study of healthy adults, four four-minute intervals at 90 to 95 percent of peak heart rate performed three times weekly increased VO2 max by 7.2 percent over eight weeks and outperformed work-matched moderate training.”

“There's a lot of exciting research right now into aging and maximum lifespan, but scientists have really just scratched the surface of the fascinating topic of how to live longer, healthier lives. Relevant Publications Rootzén, Holger, and Dmitrii Zholud.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“Dr. Patrick describes strategies you can apply immediately to enhance cellular health, protect the nervous system, elevate mood, reduce inflammation, promote muscle and bone function, and help prevent chronic disease.”

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

“Fasting can deplete the body's stores of electrolytes, especially during prolonged fasts or during periods of exercise when electrolytes can be lost during sweat. Because electrolytes are non-calories, replenishment does not appear to alter circadian rhythms.”

“While this system might have served an important function evolutionarily, today it contributes to the chronic inflammation associated with heart disease. In this clip, Dr. Ronald Krauss discusses the role of inflammation in lipoprotein metabolism.”