Related Episodes for Fasting as an evolved mechanism for repair on internal organs | Valter Longo

“In a 12-week randomized trial of 291 adults exposed to substantial air pollution, a defined broccoli-sprout beverage increased urinary excretion of glutathione-linked metabolites by 61 percent for benzene and 23 percent for acrolein.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

“While this system might have served an important function evolutionarily, today it contributes to the chronic inflammation associated with heart disease. In this clip, Dr. Ronald Krauss discusses the role of inflammation in lipoprotein metabolism.”

“1 02:37:05 - Mothers that chew xylitol gum starting mid-pregnancy and continuing until 6-12 months after birth lowered the oral streptococcus mutan bacteria, which is an anaerobic bacteria that plays a significant role in tooth decay, in their toddlers/children.”

“01:52:55 - Environmental enrichment creates epigenetic changes that benefit learning and memory in rodents and these benefits transfer to offspring. Study. 02:05:00 - NASA study showed that gravity influenced expression of genes involved in metastasis.”

“00:34:40 - Repeated traumatic brain injury has cumulative neuroinflammatory effects in the brain over years, including amyloid-beta plaque and tau tangle formation. Study. 00:44:00 - A variant of the APOE gene increases risk of developing Alzheimer’s disease as much as 15-fold.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“During sleep, the brain activates the glymphatic system, a self-cleaning process that rids the brain of metabolic byproducts. One of these byproducts is amyloid-beta, a toxic protein that aggregates and forms plaques in the brain with age and is associated with Alzheimer's disease.”

“Mitochondrial biogenesis, the formation of new mitochondria within cells, is boosted by exercise to meet heightened energy needs. While all forms of exercise can promote this process, high-intensity interval training (HIIT) might accelerate the surge in mitochondrial content more swiftly than continuous exercise.”