Ranked by shared topics, with one result from each original episode.
“Whereas fasting turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. This Aliquot features Drs. Guido Kroemer, Dominic D'Agostino, Valter Longo, Peter Attia, and Rhonda Patrick.”
“Circadian rhythms play key roles in metabolic health and ultimately influence body weight, performance, and susceptibility to diseases like diabetes and cancer. Aligning food intake with circadian rhythms can improve many aspects of metabolic health.”
“In this Aliquot, clinical psychologist Dr. Ashley Mason and sleep expert Dr. Matt Walker describe some of the behaviors that can make getting a good night's sleep difficult – and how cognitive behavioral therapy and meditation can provide help.”
“Regulating the amount of light in our environment is crucial for a good night's sleep and a good mood the next day. Habits such as using blue light-emitting electronics close to bedtime can reduce melatonin production by as much as 20 percent, impairing sleep.”
“Roughly one-quarter of people living in the US carry a genetic variant of the apolipoprotein E gene, called APOE4, the most important genetic risk factor for Alzheimer's disease. Many lifestyle behaviors can mitigate risk, especially sleep hygiene, which provides an opportunity to rid the brain of toxic metabolic byproducts that can contribute to Alzheimer's disease risk.”
“Dietary fiber is a broad term that refers to the non-digestible components of fruits and vegetables. Gut microbes break down certain types of fiber, releasing micronutrients trapped in the fiber matrix and producing beneficial metabolic byproducts, such as short-chain fatty acids.”
“Continuous glucose monitors – CGMs, for short – are wearable devices that measure blood glucose levels through a tiny sensor placed under the skin. The CGM communicates with your smartphone and provides nearly real-time information about your blood glucose levels.”
“Sugar substitutes are food products or additives that provide the sweet taste of sugar, without the calories. Evidence suggests that sugar substitutes have surprising effects on human metabolism and these effects vary person-to-person, based on the overall makeup of an individual's gut microbiome.”
“Late-night eating can have negative effects on our health. But time-restricted eating limits the daytime window during which a person eats to take advantage of the time when metabolism is optimized, improving health and even promoting weight loss.”
“Lifestyle factors, such as exercise, nutrition, sleep, and others, can temper some of the risks associated with carrying APOE4. This Aliquot focuses on the ones that can have the greatest benefits – and the ones that do the most harm.”