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Related Episodes for How light exposure affects the master clock, melatonin production and circadian rhythm

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How does time-restricted eating affect the gut microbiome | Dr. Eran Elinav

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“Normalizing the timing of food intake via time-restricted eating may help restore microbiome composition, potentially offsetting the increased disease risk. In this clip, Dr. Eran Elinav describes how the circadian rhythmicity of the microbiome is regulated and how this affects human health.”

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Dr. Valter Longo's personal approach to fasting and weight management

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“In conjunction with a restricted eating window, meal frequency can also play a role. Two meals a day may be optimal for individuals who are predisposed to gaining weight while people not prone to weight gain may prefer to eat three times a day.”

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What a Melatonin Study Found About Heart Failure

Jan 12, 2026

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

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Why Breakfast Can Support Muscle and Metabolic Health

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“In a controlled five-week crossover trial involving men with prediabetes, an early six-hour eating window with dinner before 3 p.m. improved insulin sensitivity, pancreatic beta-cell responsiveness, blood pressure, oxidative stress, and appetite without causing weight loss.”

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Melted Test Tubes! DNA methylation, a "forensically stable" measure of aging | Steve Horvath

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“The stability of DNA methylation patterns - in terms of sample reliability - makes the use of epigenetic clock data an attractive tool in the hands of researchers investigating aging around the world.”

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Aliquot #124: How much sodium do you actually need?

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“Sodium keeps our hearts beating, our muscles moving, and our nerves firing—but it's also one of the most debated nutrients in health. While sodium is essential for survival, too much or too little can tip the scales toward problems like high blood pressure or fatigue.”

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Aliquot #137: How to Optimize Iron without Causing Overload

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“In this Aliquot, I'll explore how to recognize and address iron deficiency, the unique challenges of iron overload in aging, the ways alcohol may influence brain iron, and how infants tightly regulate iron as a built-in defense against infection.”

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Aliquot #138: Why Sedation Isn't Sleep and What Actually Works

Nov 25, 2025

“From THC, CBD, alcohol, caffeine, and nicotine to melatonin, magnesium, glycine, and calming botanicals, these compounds can either support restorative sleep or subtly hijack it, changing REM, deep sleep, and circadian timing in ways we often do not feel until the next day.”

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Aliquot #51: What's the correct omega-3 dosage for maximum benefits?

Feb 5, 2022

“Since then, the body of research enumerating the profound anti-inflammatory and generalized health-promoting qualities of omega-3s continues to grow; however, some studies fail to show any effects from omega-3 supplementation.”

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Aliquot #55: Dietary strategies to improve symptoms of autoimmune disorders such as multiple sclerosis

Apr 19, 2022

“Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder that destroys myelin, the insulating layer that surrounds neurons. The causes of MS are complex and may arise from both genetic and environmental factors, including nutritional deficiencies.”

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