Related Episodes for IGF-1 and its role in diabetes and Alzheimer's | Peter Attia

“In a previous episode, entitled "Maximizing Your Mitochondria with Magnesium," we learned that 45% of the US population is deficient in magnesium and the important role magnesium plays in mitochondrial function and how this relates to exercise performance by ensuring your muscle cells have the highest oxidative capacity (ability to produce ATP or "energy") possible.”

“Dr. Huberman’s practical range is deliberately cautious: not drinking avoids the exposure, and lower weekly intake creates less burden than a drink every night or heavier episodes.”

“Sulforaphane, an isothiocyanate compound derived from broccoli sprouts and certain cruciferous vegetables, exerts a wide range of beneficial effects in humans. Some of these effects are mediated by increased glutathione, one of the body's most potent antioxidants, to promote brain health.”

“Dr. Rhonda Patrick spent many months researching and learning about the myriad factors that would influence her child's development, and she has continued to do so as her son has grown – and as new research has become available.”

“A May 2025 Nature paper showed taurine uptake may fuel aggressive myeloid leukemias in laboratory and mouse models, illustrating how nutrients beneficial to healthy tissues may also feed certain cancers.”

“In this Aliquot, Drs. Peter Attia, Stuart Phillips, Morgan Levine, Brad Schoenfeld, Michael Snyder, Valter Longo, Martin Gibala, George Church, as well as Kevin and Darya Rose and myself, share our strategies for finding our fitness.”

“However, dietary strategies, pharmaceuticals, and some supplements may reduce ApoB levels. In this Aliquot – a follow-up to Aliquot #81 – Dr. Peter Attia and I talk about some of the nutritional, pharmaceutical, and supplemental approaches to reduce ApoB.”

“For example, sulforaphane promotes the urinary excretion of benzene and acrolein, toxic compounds present in air pollution. But sulforaphane also demonstrates remarkable antibacterial activity: It reduces populations of Helicobacter pylori, or H.”

“But ultra-processing typically removes many nutrients while adding a plethora of chemicals meant to color, flavor, and preserve the food. In this Aliquot, I explain the science behind the risks associated with eating processed foods and offer advice on choosing healthier options.”

“Mitochondria are best known for their energy-producing roles, but they also help regulate cellular metabolism, signaling, and apoptosis (programmed cell death). As a result, mitochondrial health is intrinsically linked to overall health.”