Related Episodes for Ketones may preserve muscle mass during fasting | Dr. Dominic D'Agostino

“Even though the primary endpoints failed (NR did not improve insulin sensitivity or weight loss), he notes a meaningful signal in reduced liver fat—a 2% decrease in the NR group compared to a 0.2% reduction in the placebo group, a difference that didn't reach statistical significance, likely because subjects weren't randomized by liver fat and variability was high.”

“Preliminary findings from a study analyzing UK Biobank data with over 25,000 participants suggest that even 3-4 minutes of VILPA daily could reduce all-cause mortality risk by 25-30%.”

“Time-restricted eating, a form of fasting that limits the period during which a person eats to a 12- to 16-hour window, capitalizes on the benefits associated with both fasting and optimization of the body's circadian biology.”

“Timing provides a practical compromise. Dr. van Loon favors protecting the first several hours after resistance or endurance training, then placing cold exposure later in the day or on a recovery day when muscle adaptation is the priority.”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“In this short video, Rhonda talks about the new study and suggests that if you prefer your cruciferous veggies steamed, sautéed, or roasted, this strategy might offer a way to have your cooked vegetables and get your sulforaphane, too.”

“The most compelling human signal appears when the brain is under acute strain. In a randomized crossover study, a single dose of 0.35 grams per kilogram during 21 hours of sleep deprivation changed cerebral energy metabolites and preserved selected measures of cognitive performance.”

“Healthy, well-nourished adults can usually synthesize enough, and athlete trials have not found consistent improvements in immune measures, aerobic performance, body composition, or intestinal permeability from routine supplementation.”

“However, vegans and vegetarians frequently have higher levels of other micronutrients, such as vitamins C and E. Getting the required micronutrients is essential for maintaining optimal health when following a vegan diet.”