Related Episodes for Meditation changes gene expression and has long-term benefits | Roland Griffiths

“Sure, those dates on the calendar pass at the same rate for everybody, but some people appear to age slower (or faster) than others – with vastly different age-related physical changes and disease risks.”

“Geneticists like Dr. George Church, believe gene drives could be used to eliminate pathogens carried by insects, such as malaria, which is carried by a small number of mosquito species, or Lyme disease, which is carried by deer ticks.”

“Dr. Rhonda Patrick talks at SF Nerd Nite about transgenerational effects of caloric restriction on longevity, B-vitamins silencing bad genes, cognitive stimulation reversing neurodegenerative disease, exercise increases neurogenesis, and ways in which vitamin D might influence aging.”

“Osimertinib, for example, improved five-year survival among patients with resected EGFR-mutated lung cancer, while CAR-T therapy has produced durable remissions in some children and young adults with relapsed or refractory B-cell acute lymphoblastic leukemia.”

“Family-controlled research provides another view. A Swedish cohort of 2.48 million children found small associations in conventional models, but the estimates moved to the null when siblings with different prenatal exposure were compared.”

“In this talk, we’ll be exploring the intersection between genetics, nutrition, and environment: how your diet, micronutrients, exercise, heat stress, and sleep can change the expression of your genes and how this has profound effects on the way your body functions and ages.”

“New Scientist article. 02:06:10 - Some people, like Tom Cruise and Keanu Reeves, seem to defy aging. 02:08:15 - One 12-ounce can of sugar-sweetened soft drink per day shortened telomere length, corresponding to 4.6 years of biological aging.”

“Some of the factors contributing to these variable phenotypes include persistent damage to our DNA and mitochondrial dysfunction, driven by an altered NAD:NADH ratio, the latter of which has recently been shown to be improved by certain dietary supplements like nicotinamide riboside.”

“Using a Mendelian randomization analysis, scientists determined that people carrying genetic variants associated with low vitamin D levels have higher mortality from respiratory tract infections and higher all-cause mortality.”