Related Episodes for Mitophagy: a signal for mitochondrial biogenesis, metabolic adaptation, and cellular differentiation

“In this episode, Rhonda gives a summary of the science of resveratrol including its effects in animals and humans, the mechanisms behind how it works, and the bottom line on resveratrol supplementation and safety. A few key moments... For a more in-depth timeline, as well as references for this episode, click the timeline tab. Learn more about resveratrol on our overview page”

“Not only is salmon roe a good source of DHA, it also provides protein, vitamins, minerals, and astaxanthin – an antioxidant compound that gives salmon its reddish or pinkish tint. In human studies, astaxanthin reduces biomarkers of oxidative stress.”

“People that used the sauna 2-3 times per week had a 20% lower risk of Alzheimer’s disease, and those that used the sauna 4-7 times per week had a 60% lower risk of Alzheimer's disease, compared to men that used the sauna 1 time per week.”

“In this Knowledge Project excerpt, Dr. Rhonda Patrick distinguishes Finnish sauna protocols near 174–175°F from lower-temperature infrared sauna, which may require longer exposure. Dose depends on temperature, humidity, duration, acclimation, hydration, and health.”

“The comparison depends on what a dietary fat replaces. Randomized trials show that replacing palmitic acid, a common saturated fat, with unsaturated fats lowers LDL cholesterol and apolipoprotein B without a consistent effect on glucose, insulin, or C-reactive protein.”

“Although scientists have identified other lifestyle behaviors that can help prevent the build-up of amyloid plaques by boosting the capacity for glymphatic clearance – such as exercise and adequate intake of omega-3 – the most important factor by far is a good night's sleep, especially deep sleep.”

“Prolonged endurance exercise, heavy sweating, sauna use, and a minimally processed diet can also increase the practical need to replace electrolytes, which is different from routinely adding large doses for a sedentary person eating processed foods.”

“Dr. Patrick builds the strength sessions around compound movements such as squats, deadlifts, and overhead presses, then adds circuit-style exercises. She uses progressive loading, usually stops heavy lifts short of failure, and lets lighter movements move closer to failure when technique remains controlled.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“A systematic review and meta-analysis found no evidence that one time of day produces universally better improvements in health or performance, although gains can be larger when the time of training matches the time of testing.”