Related Episodes for Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration: Can We Change the Pace?

“The PROT-AGE Study Group recommends at least 1.0 to 1.2 grams of protein per kilogram of body weight per day for most adults over 65 to help maintain lean mass and physical function. Longitudinal evidence connects higher protein intake with better muscle and frailty outcomes.”

The video serves as a companion to our 15-page Sprouting Guide (https://www.foundmyfitness.com/sprouting) + Q&A with Dr. Jed Fahey (https://www.foundmyfitness.com/episodes/jed-fahey-q-a) – an illustrated manual to the basics of sprouting that includes a brief summary of the science of sulforaphane plus insights from one of the top researchers in the field of chemoprotection.

“A 2025 network meta-analysis of 217 randomized trials and 15,684 people with knee osteoarthritis found that aerobic exercise was likely the most beneficial exercise category for pain, function, gait, and quality of life.”

“In later randomized trials, urolithin A improved some laboratory measures of muscle endurance or hamstring strength, but it did not significantly improve key primary outcomes such as six-minute walk distance, muscle ATP production, or peak power.”

“Large treadmill cohorts associate higher measured fitness with lower mortality, while a 46-year study of middle-aged men linked the highest fitness category with about 4.9 additional estimated life-years compared with the lowest category.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”

“Insulin-like growth factor 1 (IGF-1) plays a role during childhood for growth and continues later in life to have anabolic and neurotrophic effects. IGF-1 is also implicated in contributing to aging and enhancing the growth of cancer after it has been initiated.”

“While it’s likely that there may be more going on with depression than just inflammation by itself, it could be an incredibly useful lens through which to look at promising avenues to potentially treat or prevent it, since controlling systemic inflammation shows promise as being both important for longevity and health in general.”

“Circulating LPS can also bind to lipoproteins, facilitating their absorption in the liver during LDL recycling, effectively removing LPS from circulation and lowering systemic inflammation – a phenomenon demonstrated mechanistically with statins that increase lipoprotein recycling by increasing LDL receptors.”

“Moringa is a tropical plant that exerts a wide range of beneficial health effects. A growing body of evidence indicates that moringin, an isothiocyanate compound derived from moringa, may help prevent or even treat a variety of chronic health conditions, including cancer, diabetes, and autism. In this clip, Dr. Jed Fahey discusses the beneficial health effects of moringa.”