Related Episodes for Reduction of inflammation from sulforaphane supplementation as a treatment for depression | Jed Fahey

“Bright light exposure has a profound effect on regulating the circadian system in humans. Dr. Panda and colleagues discovered that melanopsin — a light-sensitive protein found in specialized cells of the eye — responds to blue light and synchronizes the body's day/night cycle.”

“In this clip from Dr. Rhonda Patrick's appearance on The Dan Bongino Show, she explains that the amount of EPA and DHA needed to change the Omega-3 Index varies with baseline status, body size, formulation, diet, and adherence.”

“These transient stressors induce the expression of genes that process inflammatory molecules. In this clip, Tim Ferriss and Dr. Rhonda Patrick discuss acute versus chronic inflammation and how supplemental antioxidants can negate some of the benefits of exercise.”

“The bar was formulated to be moderate in calories (107 kcal/≈25 g bar), but nutrient dense, with a polyphenolic-rich matrix of fruit, walnuts, and non-alkali-processed dark chocolate, supplemental vitamins, minerals, docosahexaenoic acid (DHA), a blend of insoluble and soluble fibers, protein, and glutamine.”

“Chronic inflammation as a contributor to aging is not an especially new idea. Here, too, epigenetic clock evidence does seem to see this relationship. There is also evidence that HIV accelerates epigenetic aging.”

“Disruption of a person’s chronotypic schedule can influence mood, productivity, and disease risk because it may interfere with the duration of their REM sleep, which is essential for emotional well-being.”

“Dr. Patrick also revises an earlier concern about acrylamide: although roasting can form it, the human evidence she reviews does not show that ordinary coffee intake raises cancer risk, and the overall epidemiology points in the opposite direction for several cancers.”

“Other hormetic responses to cold exposure include increased production of PGC1-alpha, a protein that promotes mitochondrial biogenesis, the production of new, healthy mitochondria, and the activation of brown fat – a phenomenon once thought to occur only in newborns, but now known to occur in adults, especially after cold exposure.”

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“The majority of glutamine administered orally is taken up by the liver and gut, with little ending up in the bloodstream. Dr. D'Agostino discourages supplementing with glutamine for patients with cancers of the gastrointestinal tract and even recommends they avoid high glutamine containing foods.”