Related Episodes for The ‘Wild 5’ protocol to treat depression: exercise, diet, sleep, social connectivity & mindfulness

“When most people think about certain lifestyle factors that affect insulin sensitivity and blood glucose levels, they think about macronutrient composition, or calories, or fasting, or exercise (and lack of), but they don’t often think about sleep.”

“In this video, Dr. Rhonda Patrick interviews Dr. Terry Wahls about how she reversed her secondary-progressive multiple sclerosis with a micronutrient-dense diet and Paleo principles.”

“The pivotal role fiber plays in fueling good bacteria in the gut that act like "miniature drug factories" which produce compounds that regulate the immune system by increasing the number of T regulatory cells, which are specialized types of immune cells that keep the immune system in check and prevent autoimmune responses.”

“Robust scientific evidence indicates that consuming a plant-rich diet that provides vitamins, minerals, fiber, and phytochemicals is healthier than consuming an all-meat diet. In this clip, Dr. Jed Fahey rebuts popular claims that an all-meat diet is healthful.”

“The menus were matched for presented calories, energy density, total sugar, sodium, and fiber, but not added sugar: much more of the ultra-processed diet's sugar was added rather than contained in fruit. Protein was also only approximately matched, at about 14% versus 15.6% of calories.”

“In a short intervention in 29 healthy young men, a daily sugar-sweetened beverage increased fasting glucose, C-reactive protein, and atherogenic LDL features within three weeks; this was a biomarker study, not a cancer trial.”

“DNA-methylation clocks use patterns in blood or other tissues to estimate aspects of biological aging. In this clip from Dr. Rhonda Patrick's presentation at Natural Products Expo West, she discusses how omega-3 fatty acids may influence these research biomarkers.”

“A 2025 meta-analysis found improved quality of life, no clear overall change in ejection fraction, and a borderline improvement in New York Heart Association functional class across a small set of trials.”

“A meta-analysis restricted to direct regional measures from MRI, CT, or ultrasound found a very small average hypertrophy benefit when creatine was combined with resistance training, with uncertainty around the pooled estimate and variation across sites and populations.”

“Longer endurance aerobic exercise seems to be most effective at producing higher levels of FGF21, coinciding with anecdotes you might have heard from runners who have successfully used exercise in this sort of way. Relevant publications Flippo, Kyle H., et al.”