Search results for folate

“A 12-month randomized controlled trial found that vitamin D supplementation improved cognitive function, intelligence quotient scores, telomere length, and lowered oxidative stress markers in older adults with mild cognitive impairment (compared to placebo), suggesting that not only does vitamin D supplementation improve biomarkers of aging, but also functional outcomes.”

“The physical activity guidelines and estimates on how much activity we need are heavily based on self-reported activity, which is useful but imperfect: people remember going for a run, but they forget the short, intense bursts in daily life like sprinting up stairs, chasing kids, and running to catch a bus.”

“More than a century of research has demonstrated that nicotinamide adenine dinucleotide (NAD+) is an indispensable mediator of vital metabolic and physiological processes, including energy production, DNA synthesis and repair, and regulation of gene expression – across multiple species.”

“- Arthur Brooks, Ph.D. The episode closes with a framework from Brooks's work on the second half of life: jump, serve, worship, and connect, a framework he outlines in one of his earlier books, From Strength to Strength: "Jump" means proactively building the next thing, especially during liminal periods or unwelcome change, which Brooks sees as fertile ground for creativity.”

“Supplementing with oral DHEA (usually 25–50 mg per day) can meaningfully boost testosterone levels, potentially improving symptoms like low energy, quality of life, and libido; however, limited evidence exists for improvements in menopausal symptoms, sexual function, cognition, or overall well being in normal women without adrenal insufficiency.”

“More importantly, however, these effects were sustained – even after several months – demonstrating that sulforaphane did not exhaust the body's capacity to protect itself from environmental threats and suggesting that regular consumption of sulforaphane in foods or dietary supplements provides a kind of nutritional "seatbelt" that protects against future toxic exposures.”

“Biologically plausible strategies rooted in early medicine Against the backdrop of the devastating outcomes seen in some countries, where sudden and overwhelming spikes in case loads led to the unthinkable – a reversion to a primitive time when the modern medical system didn't exist at all – some have looked to the past for help in securing our future.”

“Because normal CRP levels (seen in most healthy adults) are typically less than 0.3 mg/dL and normal or slightly elevated levels are typically 0.3 to 1.0 mg/dL, this reduction represented a considerable change.”

“While typical muscle-oriented creatine supplementation protocols (3–5 grams daily) can benefit bone indirectly through increased muscle mass, emerging evidence suggests that higher doses (up to ~8–10 grams/day) might be optimal for maximizing creatine's potential bone benefits in aging populations, especially when paired with weight-bearing exercise.”

“- Dr. Mark Mattson https://www.foundmyfitness.com/episodes/mark-mattson/'] Whether we induce energetic crises through fasting, exercising, or tapping into a subset of the body's metabolic program through a specialized diet, some of the more compelling entities that define the ensuing metabolic switch are ketone bodies.”