Search results for autophagy

“One of the mechanisms behind the beneficial effects of exercise is its ability to induce autophagy in skeletal muscle and, potentially, other organs. In this clip, Dr. Guido Kroemer describes the anti-diabetes and anti-obesity effects of exercise-induced autophagy.”

“Emerging research suggests that caloric restriction mimetics, when used in conjunction with chemotherapy, enhance the anti-cancer immune response that makes chemotherapy have lasting effects. In this clip, Dr. Guido Kroemer describes the autophagy-inducing effects of calorie restriction mimetics such as spermidine and resveratrol.”

“Subsequently, proteins, fats, carbohydrates, and nucleic acids are released for energy and re-use. The process of autophagy is activated by cellular stressors such as nutrient depletion, hypoxia, and the presence of toxins.”

“Examples of caloric restriction mimetics include resveratrol, which is found in red wine, and spermidine, which is found in cheese. In this clip, Dr. Guido Kroemer describes the autophagy-inducing behaviors he practices as part of his healthy lifestyle.”

“An emerging strategy in the prevention and (possibly) treatment of neurodegenerative diseases is starving cells as a means to induce general autophagy to help rid the cell of protein aggregates. In this clip, Dr. Guido Kroemer describes how mitophagy contributes to the pathophysiology of neurodegenerative disease and how autophagy might mitigate these processes.”

“Reduced acetyl-CoA levels promote deacetylation of hundreds of cellular proteins that regulate the autophagic process. In this clip, Dr. Guido Kroemer discusses changes that occur within cells that signal the need to induce autophagy.”

“Autophagy is an intracellular degradation system involved in the disassembly and recycling of unnecessary or dysfunctional cellular components. Fasting – even short periods of overnight fasting that occurs during time-restricted eating – induces autophagy, providing a kind of daily maintenance for the body.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Coffee consumption is associated with protection from several chronic diseases. Coffee's beneficial effects may stem from its ability to induce autophagy; however, other evidence points to the benefits of caffeine, which can reset the body's internal clocks in the morning.”