Search results for genetics

“Age acceleration can result from intrinsic factors, such as normal metabolism and genetics, or extrinsic factors, such as diet, smoking, and exercise. Learn how epigenetic changes influence biological aging in our overview article. Read study abstract.”

“They also found that daily smoking played a role in the relationship between the genetic risk score for smoking initiation and the total gray matter volume. These findings suggest that smoking cigarettes reduces drives brain volume losses, effectively aging the brain prematurely.”

“Circadian-related genes, particularly NPAS2, have also been implicated in bipolar and major depressive disorder. For versions of 23andMe raw data that include the appropriate SNPs, this can be found in the comprehensive report at foundmyfitness.com/genetics.”

“- Peter Attia, M.D. People mentioned in this episode Helen Hobbs, MD – Researches how genetic differences cause lipid metabolism disorders. She discovered the link between a rare mutation in the PCSK9 gene and extremely low cholesterol levels, which led to the development of PCSK9 inhibitors, potent cholesterol-lowering drugs.”

“They assessed the children for autism-related behaviors when they were three to four years old. They also examined whether folic acid supplementation and MTHFR, a maternal genetic variant influencing folate metabolism, affected these associations.”

“Epigenetic alterations don't change the DNA sequence but how it is 'read.' In particular, DNA methylation, the addition of a methyl group (or molecule), is an epigenetic switch that can stably turn off genes, suggesting the potential to cause cancer just as a genetic mutation can.”

“They identified a previously unknown hormone, which they named raptin, and tracked where and when it was released. They also studied the effects of a genetic variant that blocks raptin production and examined hormone levels in people with sleep deficiency, obesity, and nighttime eating syndrome.”

“In the case of the delta variant, increased transmissibility is the result of genetic changes to the receptor binding domain, a portion of the viral spike protein. This protein enables viruses to enter cells and is the main target of SARS-CoV-2 vaccines.”

“These detrimental effects may be in part due to alterations in protein synthesis via suppression of ribosomal biogenesis. Ribosomes are organelles that translate genetic information into protein.”

“A magnesium deficiency can disrupt MMP activity, facilitating cancer cell invasion and progression. This crucial role for magnesium underscores its broad role in cellular health and cancer prevention, highlighting its importance in maintaining genetic integrity and preventing malignancies.”