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“00:20:21 - Some of the key blood-based biomarkers that are useful for tracking and projecting future cognitive health, including: homocysteine (<7μml/L preferred), which Dr. Bredesen indicates may be a mediator of cerebral atrophy, and also fasting insulin (<5% preferred), hemoglobin A1c, fasting glucose, vitamin D, and a number of other hormones relevant for trophic support.”

“Biologically plausible strategies rooted in early medicine Against the backdrop of the devastating outcomes seen in some countries, where sudden and overwhelming spikes in case loads led to the unthinkable – a reversion to a primitive time when the modern medical system didn't exist at all – some have looked to the past for help in securing our future.”

Dr. Rhonda Patrick discusses urolithin A, postmenopausal protein, microplastics, high-temperature saunas, sugar intake, and supplements for Parkinson's disease.

Dr. Rhonda Patrick discusses child nutrition, osteoporosis, cholesterol-lowering supplements, her skincare routine, and fasting versus prioritizing protein.

Dr. Rhonda Patrick discusses fragmented sleep, lipid biomarkers including ApoB and LP(a), coffee makers and bean quality, and choline supplementation.

“When produced during exercise (especially high intensity workouts like cycling, which shifts metabolism toward glycolysis to more quickly meet the high energetic demands), lactate switches on more than 600 genes involved in muscle adaptation, stimulates mitochondrial biogenesis – the process of making new mitochondria – and promotes protein synthesis, which is essential for muscle growth.”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Unique qualities of the marine omega-3 fatty acids EPA and DHA There are several omega-3 fatty acids, but the ones that have the greatest relevance for human health are the two identified in the Inuit's blood – EPA and DHA – as well as alpha-linolenic acid (ALA), which is found in a wide variety of seeds, nuts, and their oils.”

“In this Aliquot, sleep scientist Dr. Michael Grandner explains why sleep apnea is so often missed, how these nightly breathing disturbances affect the body, and which treatments can meaningfully improve sleep and long-term health.”

“- Axel Montagne, Ph.D. While we await potential breakthroughs in targeting elements of the neurovascular unit in the blood-brain barrier directly with stem cell therapeutics, gene therapies, and other cutting-edge techniques, there are things we can do now to better support vascular health and thereby help maintain the integrity of the blood-brain barrier.”