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“Diet plays a key role in the prevention of Alzheimer's disease. The Ketoflex 12/3 diet, a form of time-restrictive eating that limits the period during which a person eats to a 12-hour window at least three hours before bedtime, promotes the production of ketones.”

“"Pharmacological FGF21 signals to glutamatergic neurons to enhance leptin action and lower body weight during obesity."Molecular metabolism 64 (2022): 101564. Morville, Thomas et al. "Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans."JCI insight 3.15 (2018).”

Dr. Rhonda Patrick answers audience questions on various health, nutrition, and science topics in this Q&A session.

“Exercise is a huge driver of how well we age because it induces profound molecular shifts that support immune health and might even protect our telomeres – indicators of aging. Exercise might help forestall certain age-related diseases, such as Parkinson's disease, too.”

“The subtypes vary in their causes and manifestation, but the underlying pathological features – the accumulation of amyloid-beta plaques and tau tangles in the brain – are the same. Interestingly, amyloid-beta is both a friend and a foe, serving as a neuroprotectant in some scenarios.”

Dr. Rhonda Patrick discusses her supplement routine, Neu5Gc risks, Repatha and diabetes, heat stress, osteoporosis in men, and plyometrics.

“Dom's efforts at teasing out the differences between induced nutritional ketosis (through a low carbohydrate, high fat diet) and ketosis from the dietary introduction of exogenous ketones, like beta-hydroxybutyrate, especially in the context of therapeutic and performance enhancing effects.”

Dr. Rhonda Patrick explores creatine, dairy's effect on polyphenols, eggs' health impact, and new weight loss drugs like Ozempic in her latest Q&A.

“His targets of roughly 5–25 ng/dL free testosterone and 80–100 mg per week split into two injections are his clinical practice, not universal dosing guidance. Dr. Attia says he first puts the “house in order,” including cardiovascular risk and blood pressure.”

“Dr. Rhonda Patrick discusses how conditioning the body to heat stress through sauna use, called "hyperthermic conditioning" may cause adaptations that increase athletic endurance (by increasing plasma volume and blood flow to heart and muscles) and potentially even muscle mass. She also discusses the profound effects of hyperthermic conditioning on the brain including cognitive function.”