Search results for dopamine

“Andrew Huberman, Ph.D. on How to Improve Motivation and Focus by Leveraging Dopamine, including low-solar-angle light, morning sunlight, late-night artificial light, morning cortisol, and whether light panels can substitute for outdoor light.”

“Skin cells that are reprogrammed into neurons that produce dopamine will be transplanted into the brains of people with Parkinson’s disease in a new trial in Japan. People with Parkinson's lose dopamine-producing neurons which are involved in motor skills. Last year this technique was shown to improve disease severity in monkeys with a disease that is similar to Parkinson's disease.”

“People with Parkinson's disease that received a growth factor (GDNF) experienced a 100% improvement in dopamine uptake in a key brain region involved in the disease compared to the placebo group which did not experience any change.”

“This study suggests that the first 3 months after quitting smoking may be the most difficult because of the sustained reduction in dopamine but the good news is dopamine levels will return to normal after about 3 months. According to the CDC, 1,300 smoking-related deaths occur every day in the U.S. and, on average, smokers die 10 years earlier than nonsmokers.”

“When neurons were grown together with microglia in the lab, their responses to dopamine and glutamate (major neurotransmitter that activates neurons) were dampened, indicating that microglia can directly lower neuron responsiveness.”

“In one preclinical study, zinc chloride supplementation was found to significantly improve depression symptoms when combined with antidepressant drugs including SSRIs, tricyclic antidepressants (TCAs), and the atypical antidepressant bupropion (brand name Wellbutin), which is a norepinephrine-dopamine reuptake inhibitor (NDRI).”

“Parkinson's disease is a progressive neurodegenerative disorder that leads to the loss of dopamine-producing neurons which leads to loss of motor control. There have been a number of studies published that have shown that people with Parkinson’s disease who exercise can improve their balance and gait compared to those that do not.”

“One of the professors involved in the study said, "Like other drugs of abuse, withdrawal from chronic sucrose exposure can result in an imbalance in dopamine levels and be as difficult as going 'cold turkey' from them."”

“Whereas water immersion at warmer temperatures (90°F [32°C)]) and (68°F [20°C]) did not activate norepinephrine release, immersion at a colder temperature (57°F [14°C]) increased norepinephrine by 530 percent, dopamine by 250 percent, and energy expenditure by 350 percent, compared to pre-immersion levels.”

“Parkinson's disease is caused by the destruction of dopamine-producing neurons in the part of the brain called the substantia nigra. Dopamine is a neurotransmitter best known for its role in motor, motivation, and pleasure control.”