Biological Age Clocks
“This fits a broader theme in epigenetic aging research: the methylome can act as a biological memory system, recording signals from stress, development, inflammation, and environment long before clinical disease appears.”
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Found 400 matches across the FoundMyFitness library.
“This fits a broader theme in epigenetic aging research: the methylome can act as a biological memory system, recording signals from stress, development, inflammation, and environment long before clinical disease appears.”
“Introduction "Modulation of autophagy may represent a promising therapeutic approach for extending human lifespan and healthspan.". Homeostasis, a cell's ability to maintain a constant internal environment, is essential to cell survival.”
“Optimize your sleep environment by keeping your bedroom cool, dark, and quiet, and consider using blackout curtains or white noise machines. Limit stimulants like caffeine after mid-afternoon and minimize alcohol to protect sleep quality.”
“For activity without a scheduled workout Create opportunities for VILPA: take stairs quickly, walk a hill with purpose, carry groceries, or accelerate part of a commute. These bouts are incidental by definition, but the environment can make them more likely.”
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“For example, daytime work environments are often low light, inducing sleepiness. But bright lights from televisions or shift work environments in the evening or nighttime impair the release of melatonin, a hormone that promotes sleep, inducing wakefulness.”
“Although PCBs were banned in the 1970s, they still persist in the environment, and many freshwater, saltwater, and farmed fish are contaminated with PCBs. The amount of PCBs in salmon is considerably lower in wild-caught salmon compared to farmed salmon, and amounts are even lower in roe.”
“In a study in which investigators grew the glucosinolate-rich thale cress in warm (21°C, 70°F), moderate (15°C, 59°F), and cool (9°C, 48°F) environments, the plants grown in cool temperatures produced higher levels of glucosinolates.”
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“A growing body of evidence suggests that genes play a small role in configuring the microbiome, but the environment is the dominant factor. Dr. Elinav describes how an over-sterilized environment and exposure to antibiotics in early life may harm the microbiome.”
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“Humans have co-evolved with various microorganisms which may have had an immunologic effect on stabilizing our immune system. While sanitation and clean drinking water are critical to survival, the over sterilization of our environment may play a role in modulating the human immune system.”
“Increased intestinal permeability (also known as "leaky gut") – a condition in which gaps form between the tight junctions that join enterocytes – allows pathogens to leak through the intestinal barrier and pass directly into the bloodstream, promoting inflammation through a specialized mechanism involving detection by toll-like receptors.”
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