Search results for neurons

“Are these off-target effects simply a consequence of improved metabolic health? Dr. Ben Bikman thinks so, but also concedes to the idea that they may be having direct effects at the muscle and neurons, among other tissues.”

“Vigorous Exercise and Brain Aging Lactate—produced at high levels during vigorous exercise—mediates some of the benefits of exercise on learning and memory through its effects on BDNF expression in neurons.”

Dr. Rhonda Patrick discusses joint aging prevention, avoiding heavy metals in protein, reducing migraines, nicotinamide for skin, and minimizing jet lag.

“Perhaps the most clear-cut examples of cryotherapy’s beneficial effects are observed in the brain, where levels of the hormone and neurotransmitter norepinephrine – responsible for vigilance, attention, focus, and positive mood – increase markedly when the body is exposed to extreme cold.”

“The harder and longer you squeeze, the higher the blood pressure response. Heart rate will also increase, but this increase is driven by the brain and nervous system activity in the skeletal muscle that communicates with the brain via afferent (sensory) neurons.”

“Then they determined whether the preference for sugar (over artificial sweeteners) arises in the brain or the gut using optogenetics. Optogenetics is a research technique that allows scientists to switch a neuron's activity on or off using light and genetic engineering.”

“Dr. Huberman contrasts these with effortful pursuits, but this is a conceptual analogy rather than evidence that screens or color produce drug-equivalent dopamine changes. Large peaks can be followed by reduced drive while signaling recovers.”

“The use of alternate fuel sources allows glucose to be spared for the metabolic pathways that require it. In this clip, Dr. Dominic D'Agostino discusses the metabolic flexibility of the brain to use various substrates, including ketones, for energy.”

“In 15 people with severe traumatic brain injury, sodium lactate infusion increased brain lactate, pyruvate, and glucose without raising intracranial pressure, and a randomized study in 60 patients with mild traumatic brain injury reported better cognitive recovery than hypertonic saline.”

“A key component in these processes is the lactate shuttle – a metabolic pathway that facilitates the movement of lactate between tissues so it can be used as an energy source, effectively recycling it and supporting sustained exercise performance.”